This paper presents a study concerning the design of transmission lines using graphene. This study aims to obtain the thickness and conductivity values of graphene. These values were obtained by performing simulations of the skin effect and sheet resistance for different conductivities and thicknesses of graphene. Finally, once the values were obtained, simulations of microstrip and coplanar lines were carried out to analyze the effect of the graphene. In addition, a comparison between graphene lines and copper lines was performed.