Graphene and Co-polymer composite based molecularly imprinted sensor for ultratrace determination of melatonin in human biological fluids

Abstract

A novel molecularly imprinted polymer (MIP) sensor based on a composite of graphene (GR) and a co-polymer of 4-amino-3-hydroxy-1-naphthalenesulfonic acid (AHNSA) and melamine (MM) has been fabricated for detecting melatonin.

A Novel Hybrid Nano‐composite Grafted Electrochemically Reduced Graphene Oxide Based Sensor for Sensitive Determination of Efavirenz

“…having R 2 as 0.9878 and slope value (>0.5) further confirmed the adsorption controlled oxidation of EFZ .…”

“…Finally the residue was washed with ethanol and water and dried in the vacuum to obtain GO powder. The XRD and Raman spectra of the GO powder obtained were essentially similar as reported in the literature .…”

Nanopalladium grained polymer nanocomposite based sensor for the sensitive determination of Melatonin

“…where, R² is the correlation coefficient.The slope (dEP/dpH) has a value of 37.828 mV/pH which clearly demonstrated the involvement of an unequal number of electrons and protons in the oxidation of MEL [49]. The 2e, 1H + oxidation of melatonin in aqueous and non-aqueous media has been represented in the literature [42].…”

“…Moreover, the higher concentration of metabolites like ascorbic acid and uric acid, which are usually present in high concentration in biological fluids, interfere in the selective determination of MEL. Previously, our research group has also fabticated an molecular imprinted sensor for assaying MEL [49], but the low stability, complex multistep modification, and time consuming incubation process involved in the sensing inspires us to develop a more practical sensor by overcoming the drawbacks of molecular imprinted sensor. Thus, the purpose of the present research is to fabricate and characterize a sensor to carry out a selective and sensitive determination of MEL in biological and pharmaceutical samples.…”

A fluorescence switch sensor for detection of virginiamycin based on graphene oxide-supported carbon quantum dots and molecularly imprinted polymer

“…Due to the excellent selectivity, sensors-based on molecularly imprinted polymer (MIP) have found wide application. 4,5 Molecular imprinting technique 6 is a new and effective separation process that can prepare MIPs, 7 featuring selective recognition of a specic molecule. Thus, an MIP can be selected as the recognition template for sensor preparation.…”