Granulosa Cell Tumor In A Spayed Young Queen

Abstract

A four years old cat was presented to Clinic of Obstetrics and Gynaecology with complaints of weakness, inappetency, vomiting and estrus signs although it was spayed. Blood tests, radiography and ultrasonography revealed abdominal mass and uterine stump which were then removed surgically. Multilobular mass was defined as solid granulosa cell tumor (GCT). Increase of estrogen (E2) and insulin-like growth factor-1 (IGF-1) values were detected on the 10th postoperative day. On the 40th postoperative day, the cat was brought to Internal Medicine Clinic with the complaints of weakness, inappetency and cachexia. Anemia, leucocytosis, uremia, hyperglycemia, sensitiveness and pain in the right abdomen were determined. A tumor was detected in the liver by radiography and ultrasonography and was suspected to be GCT metastasis. Despite medical therapy, the cat died after four months. In conclusion; retained ovarian tissue after erroneous ovariohysterectomy may cause, regular estrus signs and GCT development. Even if GCTs are removed by surgical approach, they have metastatic potential that deteriorates the prognosis. Evaluating IGF-1 and E2 in the short postoperative term are beneficial for determining the metastatic potential of GCTs.

Evaluation of complete blood count in bitches with ovarian tumors: A preliminary study

“…In line with the other researchers' reports (Günay Uçmak et al, 2018;Kurban et al, 2019), the ovary affected with GCT was massive, solid and multilobular structure that had a hypoechogenic display in transabdominal ultrasonography. Although the distant metastasized organ was different, similar to the researchers' statement (Günay Uçmak et al, 2018), GCT was metastasized in this research. A benign ovarian neoplasia that was visualized in ultrasonographic examination was diagnosed as luteoma following the histopathologic examination, in this study.…”

“…One of the malignant ovarian tumors in the presented study was papillary adenocarcinoma which had an anechogenic display in the ultrasonographic examination due to the cystic structure, similar to the previous report (Diez-Bru et al, 1998). Even if GCT could occur in different animal species as queens (Günay Uçmak et al, 2018), mares (Kurban et al, 2019) and bitches, ultrasonographic images of GCTs appeared with similar characteristic. In line with the other researchers' reports (Günay Uçmak et al, 2018;Kurban et al, 2019), the ovary affected with GCT was massive, solid and multilobular structure that had a hypoechogenic display in transabdominal ultrasonography.…”

“…Even if GCT could occur in different animal species as queens (Günay Uçmak et al, 2018), mares (Kurban et al, 2019) and bitches, ultrasonographic images of GCTs appeared with similar characteristic. In line with the other researchers' reports (Günay Uçmak et al, 2018;Kurban et al, 2019), the ovary affected with GCT was massive, solid and multilobular structure that had a hypoechogenic display in transabdominal ultrasonography. Although the distant metastasized organ was different, similar to the researchers' statement (Günay Uçmak et al, 2018), GCT was metastasized in this research.…”