Granulomatous mastitis: A case report

Abstract

Idiopathic granulomatous mastitis is a rare chronic benign inflammatory mastopathy occurring mainly in young women. With a non-specific imagery, it is considered as a diagnosis by exclusion and has a challenging treatment. Histologically, it is characterized by the predominance of polynuclear neutrophils and the absence of caseous necrosis. The breast carcinoma is the main differential diagnosis at the clinical stage, and imagery plays an essential role in its diagnostic approach. Its treatment combines antibiotics, anti-inflammatories, corticosteroid therapy, and surgery. We report a 42-year-old woman who presented a breast lesion diagnosis as granulomatous mastitis based on magnetic resonance imaging, ultrasound, and histology examinations. She received a treatment with different drugs (antibiotics, anti-inflammatories). The outcome treatment was successful with a good healing of breast lesions.

Idiopathic granulomatous mastitis: A case report and literature review

“…IGM is a chronic benign breast disease observed in women of childbearing age, occurring within 5 years of the last delivery 2 . Veyssiere et al 1967 described IGM for the first time (Veyssiere 1967, as cited in Oze, 2022) 2 . The literature described that the prevalence of IGM is associated with race and region 8 .…”

“…2 Veyssiere et al 1967 described IGM for the first time (Veyssiere 1967, as cited in Oze, 2022). 2 The literature described that the prevalence of IGM is associated with race and region. 8 Its etiopathogenesis remains unsolved, that diagnostic and therapeutic are challenging.…”

“…Idiopathic granulomatous mastitis (IGM) or granulomatous lobular mastitis is a rare chronic inflammatory disease of the breast in women 1 . This disease commonly occurs shortly after a women's last pregnancy with a history of childbirth and breastfeeding that increases, especially in developing countries 2,3 . Despite the reports of an increase in the prevalence of this disease in recent years, the cause of its etiopathogenesis remains little known and diversified 3 .…”

“…1 This disease commonly occurs shortly after a women's last pregnancy with a history of childbirth and breastfeeding that increases, especially in developing countries. 2,3 Despite the reports of an increase in the prevalence of this disease in recent years, the cause of its etiopathogenesis remains little known and diversified. 3 An autoimmune or hypersensitivity reaction is the most common hypothesis regarding the etiology of the disease.…”