Granulomatous Lobular Mastitis: A Clinicopathological Study of 12 Cases

Kfoury, Hala; L, Al Bhlal

doi:10.5144/0256-4947.1997.43

Cited by 19 publications

(22 citation statements)

References 14 publications

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“…More than half of the patients are diagnosed with breast cancer until the histopathologic examination (1,20). Indeed, some patients had been exposed to mastectomy following an incorrect diagnose of malignancy as a result of false positive FNAB (7,21). Generally single breast involvement is seen, although bilateral breast involvement has been reported, and all four quadrants can be affected (4,7,8,21,22).…”

Section: Figure 2 Mammographic Imaging Of the Breast Before Treatmenmentioning

confidence: 99%

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A Challenging Entity in the Differential Diagnosis of Breast Cancer: A Retrospective Analysis of 17 Cases With Granulomatous Lobular Mastitis

Eser¹,

Kaptanoğlu²,

Kement³

et al. 2013

J Breasth Health

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Results: All the cases were women of childbearing age, who had given birth and breastfed at least once. The most common causes for admission were; breast mass in 12 patients (70.6%) and pain in 12 (70.6%) cases. Five (29.4%) cases developed a fistula and four (23.5%) had abscess requiring drainage. Mammography was used for 10 (58.8%) cases, 12 (70.6%) were examined by MRI and all the patients were evaluated with ultrasound. Five (29.4%) cases were suspicious for malignancy prior to biopsies. Diagnoses of sixteen (94.1%) cases were established with tru-cut biopsy. Fourteen (82.3%) cases underwent wide local excision (WLE) following antibiotic therapy and/or drainage and 3 (17.6%) cases with diffuse disease also underwent wide local excision following therapy with antibiotics and/or drainage and steroids (prednisolone 32 mg bid). Complete remission was observed in one patient with diffuse disease who was referred to our clinic with excisional biopsy after steroid therapy (prednisolone 32 mg bid). Relapse developed in two (11.7%) cases in the end of thirty-six months of median follow-up. Both patients were treated with steroids (prednisolone 32 mg bid). Sonuç: GLM zor tanı konulabilen ve yaygın kabul görmüş bir tedavisi olmayan selim bir meme hastalığıdır. Geniş local eksizyon uygun olgularda tek başına, yaygın tutulumu olan olgularda ise steroid tedavisi sonrası başarı ile uygulanabilir. Conclusion

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Section: Figure 2 Mammographic Imaging Of the Breast Before Treatmenmentioning

confidence: 99%

“…While being unilateral in general, rare cases of bilateral involvement have been reported (8,21,22). The location and dimensions, and the volume of the breast are important in unilateral cases.…”

Section: Figure 2 Mammographic Imaging Of the Breast Before Treatmenmentioning

confidence: 99%

A Challenging Entity in the Differential Diagnosis of Breast Cancer: A Retrospective Analysis of 17 Cases With Granulomatous Lobular Mastitis

Eser¹,

Kaptanoğlu²,

Kement³

et al. 2013

J Breasth Health

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show abstract

“…[1][2][3][4][5][6][7][8] These patients ranged in age from 11 to 80 years (mean, 35 years) and 96% (174/181) were multiparous women. The cause of GLM is unknown, but it could be related to age and pregnancy.…”

Section: Discussionmentioning

confidence: 99%

“…On the other hand, fine-needle aspiration cytology was done for 14 patients, revealing suspicious and malignant cytology in four and three patients, respectively, resulting in radical mastectomy or chemotherapy in seven patients. [1][2][3][4][5][6][7] Histological examination is considered essential for the accurate diagnosis of GLM. We now perform US-guided vacuum-assisted biopsy to identify the lobular distribution pattern because specimens can be collected easily and abundantly.…”

Section: Discussionmentioning

confidence: 99%

“…However, the disease is occasionally confused with malignancy, with reports of mastectomy or chemotherapy being performed. [1][2][3][4][5][6][7] Therefore, thorough tissue examination is a prerequisite for the differential diagnosis of GLM. Cincinnati, OH, USA), a relatively non-invasive and safe procedure, has become popular in the last decade.…”

Section: Introductionmentioning

confidence: 99%

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