1966
DOI: 10.7326/0003-4819-65-5-1081
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Granulomatous Hepatitis

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Cited by 126 publications
(11 citation statements)
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“…After this, adult worms can cause obstruction of the biliary tracts, with thickening, dilatation, and fibrosis of the segmental bile ducts. 3 The degree of hepatic destruction is consistent with the number of flukes. The overall time of vitality of mature F. hepatica worms in the liver is 10 years.…”
Section: Discussionmentioning
confidence: 49%
See 1 more Smart Citation
“…After this, adult worms can cause obstruction of the biliary tracts, with thickening, dilatation, and fibrosis of the segmental bile ducts. 3 The degree of hepatic destruction is consistent with the number of flukes. The overall time of vitality of mature F. hepatica worms in the liver is 10 years.…”
Section: Discussionmentioning
confidence: 49%
“…Diagnosis was eosinophil rich necrotizing granuloma (Figure 3). [6][7][8] Hepatic granulomatosis is seen with a large number of diseases, 3 their prevalence depends upon topography and geographical status. It may be an accidental finding on otherwise normal liver biopsy specimen.…”
Section: Discussionmentioning
confidence: 99%
“…Serum levels of liver enzymes such as aspartate aminotransferase and alanine aminotransferase were raised in 80% in tubercular group; others have reported elevated levels in 70% [4]. Abnormalities in these enzyme levels in hepatic TB patients were present in 91–94% of jaundiced group and in only 5% of the nonjaundiced patients [18]. Other parameters like serum albumin, serum globulin, albumin/globulin ratio, and gamma-glutamyl transpeptidase were considered in some of the studies [4, 5, 15] but are nonspecific for hepatic TB.…”
Section: Discussionmentioning
confidence: 99%
“…Oliva et al in his review stated that out of 15 cases of isolated tuberculoma and tubercular liver abscess, 11 had positive reactions of tuberculin skin test whereas two patients were negative and two were anergic [14]. Guckian and Perry reported 41% patients were positive for tuberculin skin test [18]. …”
Section: Discussionmentioning
confidence: 99%
“…Indeed, radioisotope scans of 17 Crohn patients re vealed half to have small spleens [9], al though splenic amyloid deposition may oc cur rarely with 2 cases out of 38 patients in one study [3]. However, splenic enlargement is frequent in sarcoid with up to 20% of patients having a palpable spleen [10] and half of 7 patients with hepatic involvement had splenomegaly [11], Thus the hepatic granulomas and splenomegaly favor the diagnosis of sarcoid not Crohn's disease. With granulomas in 3 sites, this case fulfills the criteria for sarcoidosis [2].…”
Section: Discussionmentioning
confidence: 99%