Granulomatous fasciitis followed by morphea profunda: Is granulomatous fasciitis part of a spectrum of deep morphea? A case report and review of the literature

Christensen, Angie; Loreto, Christina Di; Smitaman, Edward; Paravar, Taraneh; Jones, Karra A.; Gumá, Mónica

doi:10.1002/ccr3.1608

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2024

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“…A third report from 2019 describes a patient with morphea on the lower limbs and GA on the abdomen and dorsum of the feet 7 . Another interesting case report described the development of morphea after granulomatous fasciitis induced by Lyme 8 .…”

Section: Introduction Case Reportmentioning

confidence: 99%

Patch-Type Granuloma Annulare with Clinical and Histological Features of Morphea: A True Overlap?

et al. 2023

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A 67-year-old woman was evaluated for a worsening asymptomatic rash located on her torso, back, and legs. She denied any chills or fevers, and reported feeling otherwise well. Clinically, large brownish, slightly atrophic plaques were seen on the torso suggestive of either morphea or a granulomatous condition. Histopathologic examination revealed an increase in interstitial histiocytes infiltrating between altered collagen fibers, palisaded granulomas with increased mucin, suggestive of granuloma annulare (GA), as well as dermal sclerosis, perineural infiltrates with plasma cells and diminished CD34 counts, that are more typical for localized scleroderma/morphea. Morphea and patch-type GA may be indistinguishable clinically and share some histopathological features. This case demonstrates similarities between these conditions and features of both conditions in the same patient.

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Section: Introduction Case Reportmentioning

confidence: 99%

Patch-Type Granuloma Annulare with Clinical and Histological Features of Morphea: A True Overlap?

et al. 2023

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Eosinophilia-myalgia syndrome presenting with overlapping features of eosinophilic fasciitis and sarcoidal granulomas

Stone,

Lassen,

Abbott

et al. 2024

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Granulomatous fasciitis followed by morphea profunda: Is granulomatous fasciitis part of a spectrum of deep morphea? A case report and review of the literature

Abstract: Key Clinical MessageAlthough eosinophilic fasciitis is known to be part of the deep morphea spectrum, this first report of the coexistence of granulomatous fasciitis and morphea profunda suggests that granulomatous fasciitis may also be a part of the spectrum of deep morphea.

Cited by 2 publications

References 16 publications

Patch-Type Granuloma Annulare with Clinical and Histological Features of Morphea: A True Overlap?

Patch-Type Granuloma Annulare with Clinical and Histological Features of Morphea: A True Overlap?

Eosinophilia-myalgia syndrome presenting with overlapping features of eosinophilic fasciitis and sarcoidal granulomas

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