Abstract:Latar belakang : Granulomatosis Wegener atau granulomatosis dengan poliangiitis adalah vaskulitis nekrotikan sistemik yang menyerang pembuluh darah berukuran kecil dan sedang. Penyakit ini sering berkaitan dengan antineutrophil cytoplasmic antibodies (ANCA).Faktor pencetus terjadinya granulomatosis Wegener antara lain faktor lingkungan, infeksi, obat-obatan dan genetik. Manifestasi klinis granulomatosis Wegener dapat berupa gejala tidak spesifik seperti nyeri otot, artralgia, demam, anoreksia dan penurunan ber… Show more
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