Granulomatoses rénales : étude rétrospective de 44 observations

Pasquet, F.; Chauffer, M.; Karkowski, L.; Debourdeau, Philippe; Gregor, Brigitte Mc; Labeeuw, M; Laville, Maurice; Pavic, Michel

doi:10.1016/j.revmed.2010.04.012

Cited by 9 publications

(4 citation statements)

References 26 publications

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“…GIN caused by infection accounts for 6.6% of the total cases of GIN [1–5]. Mycobacteria and fungi are the main etiologies of the infections.…”

Section: Discussionmentioning

confidence: 99%

“…Mycobacteria and fungi are the main etiologies of the infections. Occurrences of GIN secondary to fungal infections, including Histoplasma , Candida and Cryptococcus , have been found primarily in immunocompromised patients and have been described in a few reports [1, 2, 5–16]. …”

Section: Discussionmentioning

confidence: 99%

“…Although the more common causes are drug therapy (9–45%) and sarcoidosis (9–29%) [1–5], many published studies have demonstrated that GIN can be induced by infection. Mycobacteria and fungal infections have been reported as the main infectious causes of GIN, especially in immunocompromised patients [1, 2, 5, 6, 7–16]. In such patients, GIN was reported to be one of the causes of acute kidney injury (AKI) [7–10, 11–15].…”

Section: Introductionmentioning

confidence: 99%

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Fungal granulomatous interstitial nephritis presenting as acute kidney injury diagnosed by renal histology including PCR assay

Ogura

Kagami

Nakao

et al. 2012

Clinical Kidney Journal

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We describe two cases of fungal granulomatous interstitial nephritis (GIN) presenting as acute kidney injury (AKI). Increased serum creatinine was detected in Patient 1 after chemotherapy for pharyngeal cancer and in Patient 2 after steroid pulse therapy for bronchial asthma. Renal histology of both patients revealed GIN. Polymerase chain reaction (PCR)-based detection of fungal DNA sequences from kidney tissue demonstrated Trichosporon laibachii and Candida albicans, respectively. When AKI occurs in an immunocompromised host, differential diagnosis of fungal interstitial nephritis should be considered. Furthermore, PCR-based detection of fungal DNA sequences from renal specimens can be useful for rapid diagnosis.

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“…GIN caused by infection accounts for 6.6% of the total cases of GIN [1–5]. Mycobacteria and fungi are the main etiologies of the infections.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Fungal granulomatous interstitial nephritis presenting as acute kidney injury diagnosed by renal histology including PCR assay

Ogura

Kagami

Nakao

et al. 2012

Clinical Kidney Journal

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“…Although tubulointerstitial nephritis is relatively common, GIN is rare, accounting for ∼1% of diagnoses in native renal biopsies [ 4 , 5 ]. The most common causes of GIN are sarcoidosis, drugs and infection, particularly tuberculosis [ 4 ]. Drugs implicated in cases of GIN are varied and include non-steroidal anti-inflammatory drugs, phenytoin, nitrofurantoin and vancomycin.…”

Section: Discussionmentioning

confidence: 99%

Levetiracetam-induced severe acute granulomatous interstitial nephritis

Chau

Yong

Koçyiğit

et al. 2012

Clinical Kidney Journal

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Granulomatous interstitial nephritis (GIN) is an uncommon cause of renal failure, which may be caused by drugs. Levetiracetam is an increasingly used anti-epileptic medication that is not known to cause renal toxicity in adults. To our knowledge, levetiracetam has not previously been reported as a cause of GIN. We report the case of a 69-year-old woman who developed haemodialysis-requiring acute renal failure after commencement of treatment with levetiracetam, which was shown to be GIN by renal biopsy. She made a complete recovery with cessation of levetiracetam and treatment with steroids.

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