“…9 10 Thus, a specific aetiological agent often cannot be identified despite serological, immunological, microbiological, and radiological investigations, leading to a diagnosis of ''idiopathic'' hepatic granulomas; there is a consistent cohort of such patients, accounting for approximately 15% of hepatic granuloma series. [1][2][3][4][5][6][7][8] The only published series from the UK, including one from this centre, largely included patients diagnosed before the discovery of the hepatitis C virus (HCV), now recognised as a common cause of hepatic epithelioid granulomas. 4 7 8 10 We undertook a further analysis of all liver biopsies revealing hepatic granulomas over a 10 year period, after the introduction of HCV antibody testing, to establish whether, with advances in immunological and virological testing, there has been an alteration in the distribution of diagnoses in patients identified with hepatic granulomas.…”