Granuloma faciale with disseminated extra facial lesions

Nasiri, Soheila; Rahimi, Hamzeh; Farnaghi, A; Asadi-Kani, Zahra

doi:10.5070/d37g1908g9

Cited by 19 publications

(10 citation statements)

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“…Clinically, it is characterized by single or multiple, asymptomatic, reddish-brown to violaceous papules, nodules, and plaques. The lesions are typically localized on the face, yet may uncommonly be extrafacial [6,7]. Researchers have suggested that one of the main causative factors for the disease may be sun exposure as lesions are aggravated by sunlight and favor light-exposed areas [8].…”

Section: Discussionmentioning

confidence: 99%

Unusual keloidal granuloma faciale recalcitrant to several treatments

Soufi¹,

Fawal²,

Alshehabi³

2022

Our Dermatol Online

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Granuloma faciale is a rare chronic skin disorder characterized by asymptomatic papules, nodules, and plaques on the face. Although its pathogenesis is unknown, researchers have suggested that one of the main causative factors may be sun exposure, as lesions are aggravated by sunlight and favor light-exposed areas. Herein, we are reporting the case of an adult female patient with keloidal granuloma faciale treated with a combination of several treatment methods with no improvement and a relapse. In this case, we attempted to highlight the difficulties that the doctor faces in treating the disease and to share the medical literature of our treatment experience.

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Section: Discussionmentioning

confidence: 99%

Unusual keloidal granuloma faciale recalcitrant to several treatments

Soufi¹,

Fawal²,

Alshehabi³

2022

Our Dermatol Online

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“…It usually manifests as a solitary reddish-violet plaque on the face, and extrafacial involvement may occur; other potential locations include the ears, scalp, trunk, and limbs. 1,2 Lesion size varies from several millimeters to several centimeters in diameter. The lesions are usually smooth on the surface and can often present with superficial telangiectasias and prominent follicular orifices, which sometimes show an orange peel appearance.…”

Section: Discussionmentioning

confidence: 99%

“…5 Some studies have included GF in the spectrum of IgG4-related diseases. [1][2][3][4] Although the precise pathogenesis remains unknown, interferon-γ and increased local production of interleukin 5 may be important mediators. 1…”

Section: Discussionmentioning

confidence: 99%

“…Granuloma faciale is a chronic, benign, and infrequent inflammatory skin disease of unknown origin. It usually manifests as a solitary reddish-violet plaque on the face, and extrafacial involvement may occur; other potential locations include the ears, scalp, trunk, and limbs . Lesion size varies from several millimeters to several centimeters in diameter.…”

Section: Discussionmentioning

confidence: 99%

“…In a retrospective analysis of 66 patients with GF, i27 (41.5%) patients presented with a nodule, 25 (38%) had multiple lesions, 6 (9%) had extrafacial involvement alone, and 1 (1.5%) had facial and extrafacial involvement . Some studies have included GF in the spectrum of IgG4-related diseases . Although the precise pathogenesis remains unknown, interferon-γ and increased local production of interleukin 5 may be important mediators …”

Section: Discussionmentioning

confidence: 99%

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A man in his 30s presented with a 3-month history of gradual growth of a pruriginous, reddish nodule on the left ear. He had no relevant medical history. On medical examination, a reddish, smooth, superficial nodule with small dimples and a soft consistency that measured approximately 1.5 cm in diameter was seen on the left earlobe (Figure , A). It was not painful to the touch. The patient reported no history of lesions or foreign bodies at this location. A biopsy specimen was obtained for histopathologic analysis (Figure, B and C).

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Rook's Textbook of Dermatology, Ninth Edition

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Overview Vasculitis is usually a multisystem disorder that presents in a myriad of ways. Diagnosis is based on a detailed history and careful examination. Patients may present to different specialties and their care should be led by a multidisciplinary team involving physicians with a specialist interest in vasculitis. Vasculitis can be classified by aetiology or by calibre of the vessel involved. The accepted nomenclature was defined by an international consensus meeting held in 2012; cutaneous vasculitides are considered under the umbrella of ‘single organ vasculitis’, although the classification has been expanded in this chapter. Ill‐defined entities that do not have an identified pathological basis have not been included. It should be recognized that names and classifications will change in the future with greater understanding of the underlying mechanisms of disease. The treatment of primary vasculitis involves immunosuppression. The balance between disease severity and adverse effects of treatment requires expertise and experience in management of these rare conditions. Secondary vasculitis may be due to infection, drugs, malignancy or inflammatory disease. Treating the underlying condition may resolve the vasculitis.

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Granuloma faciale with disseminated extra facial lesions

Cited by 19 publications

References 0 publications

Unusual keloidal granuloma faciale recalcitrant to several treatments

Unusual keloidal granuloma faciale recalcitrant to several treatments

Unusual Tumor on the Earlobe

Cutaneous Vasculitis

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