Granuloma faciale. Treatment with the argon laser

Apfelberg, David B.

doi:10.1001/archderm.119.7.573

Cited by 20 publications

(27 citation statements)

References 6 publications

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“…In contrast, the use of intralesional corticosteroids seems to be more effective. 5,15 Guill and Aton 14 have tried dapsone at 100 mg day )1 and van de Kerkhof 20 at 200 mg day )1 , both with good results, but these findings were not proved in other reports. 18,21,22 Pedace and Perry 3 have reported the efficacy of chloroquine.…”

Section: Discussionmentioning

confidence: 93%

Assessment of the efficacy of cryosurgery in the treatment of granuloma faciale

Παναγιωτόπουλος

Anyfantakis

Rallis

et al. 2006

British Journal of Dermatology

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Section: Discussionmentioning

confidence: 93%

Assessment of the efficacy of cryosurgery in the treatment of granuloma faciale

Παναγιωτόπουλος

Anyfantakis

Rallis

et al. 2006

British Journal of Dermatology

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“…3 The more recent use of a scanningassisted CO2 laser can however, reduce these adverse effects. 11 There are a few cases in which the argon laser was effective, 12 however, this benefit was limited by the development of collagenous scars.…”

Section: Discussionmentioning

confidence: 99%

Complete Clearance of Resistant Granuloma Faciale With Pulsed Dye Laser After Pre-treatment With Mometasone and Tacrolimus

Micallef

Boffa

2017

J Lasers Med Sci

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IntroductionGranuloma faciale is an uncommon, idiopathic, inflammatory dermatosis that usually affects the face.1 Despite its benign nature, the condition tends to be persistent, can be cosmetically distressing and is notoriously difficult to eradicate completely. 2 We report a case of successful treatment of granuloma faciale using 595-nm pulsed dye laser following topical mometasone and tacrolimus. Case PresentationA 39-year-old English lady with Fitzpatrick skin phototype II, presented to our Dermatology Department with 3 sharply-demarcated, reddish-brown, indurated plaques with accentuated follicular openings and few superficial telangiectases. These were present on both cheeks and the tip of the nose. The patient had been previously diagnosed with granuloma faciale in the United Kingdom 6 months previously and was started on dapsone 50 mg daily, to which there was no visible response. The patient then moved to Malta where dapsone was stopped and the lesion on the right cheek biopsied. The biopsy showed a dense neutrophilic and eosinophilic infiltrate within the papillary and reticular dermis, with a prominent Grenz zone, confirming the diagnosis of granuloma faciale. At this point, treatment with pulsed dye laser was attempted. A test area in the right cheek lesion underwent two treatments with a ScleroPlus pulsed dye laser (Candela Corporation, Wayland, Mass) with cryogenspray dynamic cooling. A wavelength of 595 nm and pulse duration of 1.5 ms were used, with a 7 mm spot at a fluence of 8.5 J/cm 2 for the first session and 9.5 J/ cm 2 for the second session, carried out after an interval of 8 weeks. There was no visible improvement with this treatment. The patient was lost to follow-up but re-presented 5 years later with the same lesions, which by then had become more prominent. She was prescribed mometasone 0.1% ointment once daily for 2 months, with no visible improvement. Tacrolimus 0.1% ointment twice daily was then added to the mometasone ointment for another 2 Case Report Abstract Introduction: Granuloma faciale is an uncommon inflammatory dermatosis which usually affects the face and is often resistant to treatment. Case Report: A 39-year-old English lady with Fitzpatrick skin phototype II presented with typical lesions of granuloma faciale, confirmed on biopsy, on her cheeks and nose. Treatment with ScleroPlus pulsed dye laser (Candela Corporation, Wayland, Mass) produced no visible improvement. The patient re-presented 5 years later with the same lesions, now more prominent. No improvement was noted with topical mometasone, however addition of topical tacrolimus caused significant flattening. Since the erythema and telangiectases persisted, treatment with ScleroPlus pulsed dye laser was re-attempted. Treatments were performed with a wavelength of 595 nm, pulse duration of 1.5 ms and 7 mm spot at a fluence of 8.5 J/cm2 in the first session and 9.5 J/cm 2 in the subsequent 2 sessions. This resulted in complete resolution without scarring or pigmentary change. There was no recurrence at follow-up ...

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“…7 The carbon dioxide and argon lasers have also been shown to be successful in treating GF. 8,9 However, these lasers have been associated with post-procedure scarring. The wavelengths emitted by argon lasers (480-520 nm) have a more selective photothermolysis effect on oxyhaemoglobin than carbon dioxide lasers but they are disadvantaged by having a continuous pulse duration.…”

Section: Reportmentioning

confidence: 99%

Granuloma faciale treated with the pulsed-dye laser: a case series

Cheung

Lanigan

2005

Clin Exp Dermatol

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Granuloma faciale (GF) is a rare cutaneous condition of unknown origin with characteristic clinicopathological features. It predominantly affects the face and in some causes an unacceptable cosmetic appearance. Numerous medical and surgical treatments have been used with varying degrees of success. Several single-patient case reports have demonstrated the successful use of the pulsed dye laser (PDL) in treating GF. This study assesses the results of four patients with facial GF from one dermatological laser centre that were treated with the Candela Vbeam PDL at 595 nm. Resolution of the GF was achieved in only two of the four patients (50%). Nevertheless this study provides further evidence that the PDL can help some patients with GF. Subsequently it is still a valuable treatment option for GF, especially as it is safe, well tolerated and quick.

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Granuloma faciale. Treatment with the argon laser

Cited by 20 publications

References 6 publications

Assessment of the efficacy of cryosurgery in the treatment of granuloma faciale

Assessment of the efficacy of cryosurgery in the treatment of granuloma faciale

Complete Clearance of Resistant Granuloma Faciale With Pulsed Dye Laser After Pre-treatment With Mometasone and Tacrolimus

Granuloma faciale treated with the pulsed-dye laser: a case series

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