Granular Hydrogels Improve Myogenic Invasion and Repair after Volumetric Muscle Loss
Gabrielle I. Tanner,
Leia Schiltz,
Niharika Narra
et al.
Abstract:Skeletal muscle injuries including volumetric muscle loss (VML) lead to excessive tissue scarring and permanent functional disability. Despite high prevalence, there is currently no effective treatment for VML. Bioengineering interventions such as biomaterials that fill the VML defect to support cell and tissue growth are a promising therapeutic strategy. However, traditional biomaterials developed for this purpose lack the pore features needed to support cell infiltration. The present study investigates for t… Show more
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