Granular Cell Tumors of the Larynx: A Clinicopathologic Study of Five Patients

Valldeperes, Ariadna; Thomas-Arrizabalaga, Izaskun; Alvarez-Ceballos, Leire; Landa, Mikel

doi:10.1016/j.jvoice.2019.04.017

Cited by 6 publications

(9 citation statements)

References 15 publications

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“…Granular cell tumor was first described in 1926 [7] . The first theory suggested a myogenic origin, ruled today ruled out by the presence of the tumor in areas without muscle fibers and the absence of myoglobin in the granular cells [8] .…”

Section: Discussionmentioning

confidence: 99%

Granular cell tumor of the vocal cord: Case Report and Literature Review

Cura

Labedz

Uomini

et al. 2022

International Journal of Surgery Case Reports

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Section: Discussionmentioning

confidence: 99%

Granular cell tumor of the vocal cord: Case Report and Literature Review

Cura

Labedz

Uomini

et al. 2022

International Journal of Surgery Case Reports

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“…Die Prädilektionsstelle innerhalb des Kehlkopfes ist der posteriore Anteil der Stimmlippen (▶ Abb. 9) [158]. Die Tumoren imponieren als blasse, submukös wachsende Masse auf den Stimmlippen, das Leitsymptom ist die Dysphonie [159].…”

Section: Klinisches Erscheinungsbildunclassified

“…The predilection site within the larynx is the posterior part of the vocal folds ( Fig. 9 ) 158 . The tumors impose as pale, submucously growing mass on the vocal folds, the initial symptom is dysphonia 159 .…”

Section: Benign Tumorsmentioning

confidence: 99%

Seltene Erkrankungen des Larynx, der Trachea und der Schilddrüse

Hackenberg¹,

Kraus²,

Scherzad³

2021

Laryngorhinootologie

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ZusammenfassungDer Übersichtsartikel beinhaltet eine Zusammenstellung seltener Erkrankungen von Larynx, Trachea und Schilddrüse. Im Speziellen werden angeborene Fehlbildungen, seltene Formen der entzündlichen Larynxerkrankungen, gutartige und bösartige epitheliale sowie nicht-epitheliale Tumoren, laryngeale und tracheale Manifestationen von Allgemeinerkrankungen und schließlich seltene Erkrankungen der Schilddrüse besprochen. Die einzelnen Kapitel beinhalten eine Übersicht über die Datenlage in der Literatur, das jeweilige klinische Erscheinungsbild, wichtige Stichpunkte zur Diagnostik und zur Therapie und eine abschließende Stellungnahme zur Prognose der Erkrankung. Des Weiteren finden sich Hinweise zu Studienregistern und Selbsthilfegruppen.

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“…Granular cell tumors are most frequently encountered in patients in their third to sixth decades of life and are uncommon in children. There appears to be a higher incidence among African-Americans and females, although laryngeal involvement is more prevalent in males [2][3][4]. Exact world statistics are not adequately established and most of the literature, including the laryngeal presentation of granular cell tumors, consists of a few case reports.…”

Section: Introductionmentioning

confidence: 99%

“…These tumors can arise in any part of the body, but 50% of cases occur in the head and neck region, with the tongue being the most common location. Around 3-10% of all cases occur in the larynx [ 2 , 3 ].…”

Section: Introductionmentioning

confidence: 99%

Rare Case of Pediatric Upper Airway Obstruction: Laryngeal Granular Cell Tumor

Mirambeaux¹,

Paulino²,

Acra-Tolari³

et al. 2022

Cureus

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Granular cell tumors (GCTs) are uncommon neoplasms of unknown origin that can manifest in multiple locations throughout the body. Physicians should be aware of this type of tumor presenting in unusual locations such as the larynx, particularly in pediatric patients with stridor and dysphonia. We describe an 11year-old female with a large laryngeal mass that obstructed the majority of the laryngeal lumen. A tracheotomy was performed to secure the patient's airway, followed by a direct suspension laryngoscopy, during which the mass was excised in its entirety. The biopsied mass was histopathologically and immunohistochemically examined to confirm the diagnosis of granular cell tumor. She benefited from treatment and experienced a favorable outcome. This case report emphasizes the critical nature of properly diagnosing this type of tumor in patients who present with vocal or respiratory symptoms.

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Granular Cell Tumors of the Larynx: A Clinicopathologic Study of Five Patients

Cited by 6 publications

References 15 publications

Granular cell tumor of the vocal cord: Case Report and Literature Review

Granular cell tumor of the vocal cord: Case Report and Literature Review

Seltene Erkrankungen des Larynx, der Trachea und der Schilddrüse

Rare Case of Pediatric Upper Airway Obstruction: Laryngeal Granular Cell Tumor

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