Granular cell tumor of the common bile duct: A Japanese case

Abstract

Granular cell tumor (GCT) of the biliary system is rare. It is reported that it occurs more commonly in young black women. We report here our seldom experience of a Japanese case in whom icterus was found as a first symptom just after a caesarean operation. A 36-year-old Japanese woman developed icterus after delivery by the Caesarean operation. A surgical operation was performed without can deny that there was a tumor-related change in a bile duct as a result of examination for various images. As a result of pathological evaluation, GCT was diagnosed. By the preoperative organization biomicroscopy result, it was not able to be attachd a right diagnosis. It was thought that this tumor, although rare, should be considered as one of the causes of biliary stenosis in the younger population.

Granular Cell Tumor of the Common Bile Duct: A Case Report of a Rare Anatomical Entity and Brief Review of the Literature

“…They are infrequently located in the gastrointestinal tract, and rarely located in the biliary tree (< 1%) [2,3,7,9,11]. GCTs are related to the peripheral nerves, and it is generally accepted that they have a neurogenic origin and arise from Schwann cells [1][2][3][4][5][7][8][9][10][11]. Thus far, few cases of GCTs in the extrahepatic biliary tree have been reported, but no author has ever reported a malignant GCT in the biliary system [1][2][3][4][5][7][8][9][10][11].…”

“…GCTs are related to the peripheral nerves, and it is generally accepted that they have a neurogenic origin and arise from Schwann cells [1][2][3][4][5][7][8][9][10][11]. Thus far, few cases of GCTs in the extrahepatic biliary tree have been reported, but no author has ever reported a malignant GCT in the biliary system [1][2][3][4][5][7][8][9][10][11]. GCTs of the biliary tree are usually found in young African-American females between 30 and 40 years of age [1][2][3][7][8][9][10].…”

“…Granular cell tumors (GCTs) of the biliary tree are extremely rare, and according to the literature, are always benign [1][2][3][4][7][8][9][10]. GCTs are usually located in the skin, subcutaneous tissues, oral cavity, head, and neck [2,7,8,11].…”

“…Tumors of the biliary tree are usually malignant, with a poor prognosis, while benign tumors of the biliary tree are rare [1][2][3][4][5][6]. Granular cell tumors (GCTs) of the biliary tree are extremely rare, and according to the literature, are always benign [1][2][3][4][7][8][9][10].…”

“…GCTs are usually located in the skin, subcutaneous tissues, oral cavity, head, and neck [2,7,8,11]. They are infrequently located in the gastrointestinal tract, and rarely located in the biliary tree (< 1%) [2,3,7,9,11]. GCTs are related to the peripheral nerves, and it is generally accepted that they have a neurogenic origin and arise from Schwann cells [1][2][3][4][5][7][8][9][10][11].…”