Graft-versus-host disease: Therapeutic prospects of improving the long-term post-transplant outcomes

Kurya, Abdulaziz Umar; Aliyu, Usama; Tudu, Abdulrahman Ibrahim; Usman, A.G; Yusuf, Mohammad; Gupta, Suneel; Ali, Aleem Azal; Gulfishan, Mohd; Singh, Santosh Kumar; Hussain, Imran; Gusau, Mu'azu Abubakar

doi:10.1016/j.tpr.2022.100107

Cited by 3 publications

(1 citation statement)

References 62 publications

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“…19 Furthermore, even high-grade CIN 2 in adolescents regresses 60% of the time within the first three years, indicating a substantial likelihood of self-resolution and other relevant infectious diseases. [20][21][22][23][24] These advancements in understanding HPV dynamics and the distinct risks associated with various strains are propelling the field toward more precise and tailored screening strategies for the prevention of cervical cancer. Cancer Screen Prev populations with limited access to quality healthcare services.…”

Section: Global Impact Of Cervical Cancer On Women's Healthmentioning

confidence: 99%

Perspectives on Cervical Cancer: Insights into Screening Methodology and Challenges

Yusuf

2024

Cancer Screen Prev

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Cervical cancer is a significant public health concern worldwide. Current screening approaches include Pap smears, human papillomavirus testing, visual inspections, and emerging molecular techniques, aimed at enhancing precision and accessibility. The landscape also includes the increasing prominence of self-sampling and telemedicine, which broaden the reach of screening services. Human papillomavirus vaccination programs targeting young girls have the potential to significantly reduce long-term risk. These evolving strategies are supported by global initiatives such as the World Health Organization's Cervical Cancer Elimination Initiative, aiming to increase screening efforts and reduce the global impact of cervical cancer. The key findings of this study suggested that current methodologies for the detection and prevention of cervical cancer are a little beneficial and there is a pressing need to use advanced technologies such as highly sophisticated equipment integrated with artificial intelligence. In addition, the detection of cervical cancer screening provides insights into evolving methodologies, promising prospects, and nuanced challenges that must be addressed to prevent this condition in females worldwide. Looking forward, future cervical cancer screening involves further refinements in molecular testing, expanded vaccine coverage, and the integration of telehealth solutions, promising increased accessibility and improved early detection to overcome insightful challenges.

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Section: Global Impact Of Cervical Cancer On Women's Healthmentioning

confidence: 99%

Perspectives on Cervical Cancer: Insights into Screening Methodology and Challenges

Yusuf

2024

Cancer Screen Prev

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Liver Pathology After Hematopoietic Stem Cell Transplantation

Phansalkar

Kambham

Charu

2023

Surgical Pathology Clinics

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Therapeutic Perspective of Natural Alkaloids in Cervical Cancer Management

Jadhao,

Parveen,

Yusuf

2024

Jabirian J. Biointerface Res. Pharmaceut. Appl. Chem.

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Cervical cancer is a major global public health concern that requires continuous advancements in screening methodologies and the management of associated challenges. This will make cervical cancer a preventable and treatable condition for women across the world. In this review, we explore the therapeutic potential of natural alkaloids in managing cervical cancer. These compounds are derived from diverse sources such as plants and marine organisms. They demonstrate multifaceted mechanisms, including anti-proliferative, anti-angiogenic, and immunomodulatory effects. Preclinical studies have shown their efficacy on cervical cancer cell lines, while clinical trials have showcased their potential inpatient interventions. To enhance their efficacy, synergistic approaches combining alkaloids with conventional treatments are being considered. Despite challenges such as bioavailability and toxicity, continued research is vital to unlocking the full potential of natural alkaloids. This will offer novel and complementary strategies in cervical cancer therapeutics.

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Graft-versus-host disease: Therapeutic prospects of improving the long-term post-transplant outcomes

Cited by 3 publications

References 62 publications

Perspectives on Cervical Cancer: Insights into Screening Methodology and Challenges

Perspectives on Cervical Cancer: Insights into Screening Methodology and Challenges

Liver Pathology After Hematopoietic Stem Cell Transplantation

Therapeutic Perspective of Natural Alkaloids in Cervical Cancer Management

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