“…Continuity equation method offers an indirect AVA estimation, based on the principle of conservation of the mass, which uses the quantitative analysis of the transvalvular aortic flows through phase contrast sequences (PC-MRI) acquired in the valve plane (AVA = stroke vol/velocity-time integral at the aortic flow velocity peak). 33 Multimodality comparisons showed no differences between AVA measurements obtained by CMR versus 2D TTE, three-dimensional (3D) TTE, Doppler echocardiography, TEE and ICA 29,34,35 whereas both 2D TTE and ICA underestimated valve annulus dimensions compared to CMR (p < 0.01). 29 Moreover, the sensitivity and specificity of CMR to detect AVA ≤0.80 cm 2 , compared with catheterization, were 78 and 89%, which are higher than TEE (70 and 70%) and TTE (74 and 67%), 34 respectively.…”