Gradients of Orientation, Composition, and Hydration of Proteins for Efficient Light Collection by the Cornea of the Horseshoe Crab

Spaeker, Oliver; Taylor, Gavin J.; Wilts, Bodo D.; Slabý, Tomáš; Abdel‐Rahman, Mohamed Ashraf Khalil; Scoppola, Ernesto; Schmitt, Clemens N. Z.; Sztucki, Michael; Liu, Jiliang; Bertinetti, Luca; Wagermaier, Wolfgang; Scholtz, Gerhard; Fratzl, Peter; Politi, Yael

doi:10.1002/advs.202203371

Cited by 4 publications

(1 citation statement)

References 47 publications

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“…The ray tracing is based on the Helmholtz equation (Equation 1 ) to design and simulate the performance of TF, which is used to accurately analyze the propagation process of light. [ 16 ] The tip diameter of TF was fixed as 10 µm, and the taper angle φ (4.7–10.2) was regulated by the taper length L (0.25‐0.5 mm) according to Equation 2 . The materials forming all the components of the TFs and the surrounding media were assumed to be homogenous (refractive index constant in space).…”

Section: Resultsmentioning

confidence: 99%

A High‐Density Raman Photometry for Tracking and Quantifying of AchE Activity in The Brain of Freely Moving Animals with Network

Zhang,

Liu,

et al. 2023

Advanced Science

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A high‐density Raman photometry based on a dual‐recognition strategy is created for accurately quantifying acetylcholinesterase (AchE) activity in 24 brain regions of free‐moving animals with network. A series of 5‐ethynyl‐1,2,3,3‐tetramethyl‐based molecules with different conjugated structures and substitute groups are designed and synthesized for specific recognition of AchE by Raman spectroscopy. After systematically evaluating the recognition ability toward AchE, 2‐(4‐((4‐(dimethylamino)benzoyl)oxy)styryl)‐5‐ethynyl‐1,3,3‐trimethyl‐3H‐indol‐1‐ium (ET‐5) is finally optimized for AchE determination, which shows the highest selectivity, the greatest sensitivity, and the fastest response time among the investigated seven molecules. More interestingly, using the developed probe for AchE with high accuracy and sensitivity, the optimized AchE regulated by nitric oxide (NO) is discovered for promoting the neurogenesis of neural stem cells (NSCs). Benefiting from the high‐density photometry, it is found that the activity and distribution of AchE varied in 24 brain regions, and the levels of AchE activity in 24 brain regions of Alzheimer's mice (AD) are lower than those of normal mice. It is the first time that a functional network of AchE in 24 brain regions is established. It is also found that the loss of AchE functional network in AD mice is restored and reconstructed by the controlled release of AchE regulated by NO.

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Section: Resultsmentioning

confidence: 99%

A High‐Density Raman Photometry for Tracking and Quantifying of AchE Activity in The Brain of Freely Moving Animals with Network

Zhang,

Liu,

et al. 2023

Advanced Science

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Biopolymer Photonics: From Nature to Nanotechnology

Vogler‐Neuling,

Saba,

Gunkel

et al. 2023

Adv Funct Materials

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Biopolymers offer vast potential for renewable and sustainable devices. While nature mastered the use of biopolymers to create highly complex 3D structures and optimized their photonic response, artificially created structures still lack nature's diversity. To bridge this gap between natural and engineered biophotonic structures, fundamental questions such as the natural formation process and the interplay of structural order and disorder must be answered. Herein, biological photonic structures and their characterization techniques are reviewed, focusing on those structures not yet artificially manufactured. Then, employed and potential nanofabrication strategies for biomimetic, bio‐templated, and artificially created biopolymeric photonic structures are discussed. The discussion is extended to responsive biopolymer photonic structures and hybrid structures. Last, future fundamental physics, chemistry, and nanotechnology challenges related to biopolymer photonics are foreseen.

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Calcitic Prisms of The Giant SeashellPinna NobilisForm Light Guide Arrays

et al. 2023

Self Cite

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The shells of the Pinnidae family are based on a double layer of single‐crystal‐like calcitic prisms and inner aragonitic nacre, a structure known for its outstanding mechanical performance. However, on the posterior side, shells are missing the nacreous layer, which raises the question of whether there can be any functional role in giving up this mechanical performance. Here, it is demonstrated that the prismatic part of the Pinna nobilis shell exhibits unusual optical properties, whereby each prism acts as an individual optical fiber guiding the ambient light to the inner shell cavity by total internal reflection. This pixelated light channeling enhances both spatial resolution and contrast while reducing angular blurring, an apt combination for acute tracking of a moving object. These findings offer insights into the evolutionary aspects of light‐sensing and imaging and demonstrate how an architectured optical system for efficient light‐tracking can be based on birefringent ceramics.

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Gradients of Orientation, Composition, and Hydration of Proteins for Efficient Light Collection by the Cornea of the Horseshoe Crab

Cited by 4 publications

References 47 publications

A High‐Density Raman Photometry for Tracking and Quantifying of AchE Activity in The Brain of Freely Moving Animals with Network

A High‐Density Raman Photometry for Tracking and Quantifying of AchE Activity in The Brain of Freely Moving Animals with Network

Biopolymer Photonics: From Nature to Nanotechnology

Calcitic Prisms of The Giant SeashellPinna NobilisForm Light Guide Arrays

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