Graded morphogenetic patterns during the development of the extraembryonic blood system and coelom of the chick blastoderm: A scanning electron microscope and light microscope study

Kessel, Joan; Fabian, Barry

doi:10.1002/aja.1001730204

Cited by 33 publications

(13 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A similar model for the early separation of cells contributing to the BC/EC lineage and cells contributing to the extraembryonic coelomic linings was proposed by Sabin (Sabin, 1920), although the SMC nature of coelomic lining cells was not clearly mentioned in that report. The general anatomical organization, proposed in this work, of the extraembryonic mesoderm in the chick embryo, is also supported by ultrastructural studies (Kessel and Fabian, 1985;Murphy and Carlson, 1978).…”

Section: Research Articlesupporting

confidence: 54%

“…1A). The BC/EC progenitors aggregate to form blood islands within the extraembryonic splanchnic mesoderm, which contains in addition vascular SMCs (Kessel and Fabian, 1985;Murphy and Carlson, 1978;Sabin, 1920). The extraembryonic somatic mesoderm gives rise to mesothelial cells lining the ectoderm, from which the amnionic and chorionic membranes are derived (Adamstone, 1948;Oppenheim, 1966;Pierce, 1933;Romanoff, 1960;Wu et al, 2001).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Notch mediates Wnt and BMP signals in the early separation of smooth muscle progenitors and blood/endothelial common progenitors

Shin¹,

Nagai²,

Sheng³

2009

Development

View full text Add to dashboard Cite

During embryonic development in amniotes, the extraembryonic mesoderm, where the earliest hematopoiesis and vasculogenesis take place, also generates smooth muscle cells (SMCs). It is not well understood how the differentiation of SMCs is linked to that of blood (BCs) and endothelial (ECs) cells. Here we show that, in the chick embryo, the SMC lineage is marked by the expression of a bHLH transcription factor, dHand. Notch activity in nascent ventral mesoderm cells promotes SMC progenitor formation and mediates the separation of SMC and BC/EC common progenitors marked by another bHLH factor, Scl. This is achieved by crosstalk with the BMP and Wnt pathways, which are involved in mesoderm ventralization and SMC lineage induction, respectively. Our findings reveal a novel role of the Notch pathway in early ventral mesoderm differentiation, and suggest a stepwise separation among its three main lineages, first between SMC progenitors and BC/EC common progenitors, and then between BCs and ECs.

show abstract

Section: Research Articlesupporting

confidence: 54%

Section: Introductionmentioning

confidence: 99%

Notch mediates Wnt and BMP signals in the early separation of smooth muscle progenitors and blood/endothelial common progenitors

Shin¹,

Nagai²,

Sheng³

2009

Development

View full text Add to dashboard Cite

show abstract

“…The splanchnic wall of the extraembryonic coelom is the source of cells for the vascular smooth muscle layer during vasculogenesis, and after formation of the vascular network, vascular smooth muscle layer is in direct contact with the extraembryonic coelomic cavity. This general organization of somatopleural and splanchnopleural tissues in the yolk sac is supported by ultrastructure studies (Kessel and Fabian, 1985;Murphy and Carlson, 1978).…”

Section: Extraembryonic Mesoderm and Ventral Mesodermmentioning

confidence: 53%

Primitive and definitive erythropoiesis in the yolk sac: a birds eye view

Sheng¹

2010

Int. J. Dev. Biol.

View full text Add to dashboard Cite

The yolk sac is the sole niche and source of cells for primitive erythropoiesis from E1 to E5 of chicken development. It is also the main niche and source of cells for early definitive erythropoiesis from E5 to E12. A transition occurs during late embryonic development, after which the bone marrow becomes the major niche and intraembryonically-derived cells the major source. How the yolk sac is involved in these three phases of erythropoiesis is discussed in this review. Prior to the establishment of circulation at E2, specification of primitive erythrocytes is discussed in relation to that of two other cell types formed in the extraembryonic mesoderm, namely the smooth muscle and endothelial cells. Concepts of blood island, hemangioblast and hemogenic endothelium are also discussed. It is concluded that the chick embryo remains a powerful model for studying developmental hematopoiesis and erythropoiesis.

show abstract

“…However, the first blood vessels within the embryo always form in mesoderm that is in close proximity to endoderm (Mato et al, 1964;Wilt, 1965;Gonzalez-Crussi, 1971;Mobbs and McMillan, 1979;Meier, 1980;Kessel and Fabian, 1985;Pardanaud et al, 1989). Furthermore, we have recently demonstrated that a signal originating from the endoderm is essential for the assembly of angioblasts into tubes (Vokes and Krieg, 2002a).…”

Section: Introductionmentioning

confidence: 99%

Hedgehog signaling is essential for endothelial tube formation during vasculogenesis

et al. 2004

View full text Add to dashboard Cite

During embryonic development, the first blood vessels are formed through the aggregation and subsequent assembly of angioblasts (endothelial precursors) into a network of endothelial tubes, a process known as vasculogenesis. These first vessels generally form in mesoderm that is adjacent to endodermal tissue. Although specification of the angioblast lineage is independent of endoderm interactions, a signal from the endoderm is necessary for angioblasts to assemble into a vascular network and to undergo vascular tube formation. In this study, we show that endodermally derived sonic hedgehog is both necessary and sufficient for vascular tube formation in avian embryos. We also show that Hedgehog signaling is required for vascular tube formation in mouse embryos, and for vascular cord formation in cultured mouse endothelial cells. These results demonstrate a previously uncharacterized role for Hedgehog signaling in vascular development, and identify Hedgehog signaling as an important component of the molecular pathway leading to vascular tube formation.

show abstract

Graded morphogenetic patterns during the development of the extraembryonic blood system and coelom of the chick blastoderm: A scanning electron microscope and light microscope study

Cited by 33 publications

References 14 publications

Notch mediates Wnt and BMP signals in the early separation of smooth muscle progenitors and blood/endothelial common progenitors

Notch mediates Wnt and BMP signals in the early separation of smooth muscle progenitors and blood/endothelial common progenitors

Primitive and definitive erythropoiesis in the yolk sac: a birds eye view

Hedgehog signaling is essential for endothelial tube formation during vasculogenesis

Contact Info

Product

Resources

About