Grade of chronic renal failure, and acute and long-term outcome after percutaneous coronary interventions

Reinecke, Holger; Trey, Torsten; Matzkies, F; Fobker, Manfred; Breithardt, Günter; Schaefer, Roland M.

doi:10.1046/j.1523-1755.2003.00784.x

Cited by 94 publications

(57 citation statements)

References 19 publications

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“…Reinecke et al 19 indicated that long-term mortality increased with higher creatinine levels, with a significant difference starting at a level of 1.3 mg/dl and higher. They claimed that the decrease in renal function might represent a sensitive indicator of general microangiopathy induced by the presence of cardiovascular risk factors, particularly hypertension and diabetes.…”

Section: Discussionmentioning

confidence: 99%

Serum Creatinine on Admission Predicts Long-Term Mortality in Acute Myocardial Infarction Patients Undergoing Successful Primary Angioplasty

Yamaguchi

Kasanuki

Ishii

et al. 2007

Circ J

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Background Data about the long-term mortality of acute myocardial infarction (AMI) patients with renal insufficiency who received sufficient early revascularization are scant, so the present study evaluated the impact of serum creatinine levels on the long-term mortality in patients with AMI undergoing successful primary percutaneous coronary intervention (PCI). Methods and ResultsThe Heart Institute of Japan Acute Myocardial Infarction (HIJAMI) registry has 3,021 consecutive AMI patients. Primary PCI was attempted in 1,451 patients and successful revascularization was obtained in 1,359 patients (93.6%). An elevated serum creatinine level, defined as creatinine ≥1.2 mg/dl, was observed in 216 patients (15.8%). Univariate analyses showed statistical differences between normal and elevated serum creatinine groups in age, gender, hypertension, previous myocardial infarction, number of diseased vessels and Killip class. During a median follow-up period of 39 [32][33][34][35][36][37][38][39][40][41][42][43][44][45][46][47][48][49] months, the event-free survival rate was lower in elevated creatinine group than normal creatinine group. Multivariate Cox proportional hazards model showed that serum creatinine level was an independent predictor of long-term mortality (adjusted hazard ratio 1.43 [95% confidence interval 1.03-1.99]). Conclusion The serum creatinine level on admission in patients with AMI predicts long-term mortality, even in those with successful primary PCI. (Circ J 2007; 71: 1354 -1359

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Section: Discussionmentioning

confidence: 99%

Serum Creatinine on Admission Predicts Long-Term Mortality in Acute Myocardial Infarction Patients Undergoing Successful Primary Angioplasty

Yamaguchi

Kasanuki

Ishii

et al. 2007

Circ J

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“…Previous studies have reported that patients with CKD are at increased risk of adverse cardiac events after stent implantation, 28,29 and the incidence of stent thrombosis was also reported to be associated with CKD after DES implantation. 30 However, there has been no study showing the association between NA and CKD.…”

Section: Ckd and Namentioning

confidence: 98%

Predictors for Neoatherosclerosis

Yonetsu

Katô

Kim

et al. 2012

Circ: Cardiovascular Imaging

152

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Optical coherence tomography (OCT) is an emerging intracoronary diagnostic modality that provides high-resolution images of coronary artery in vivo. 11 In addition to tissue characterization in native coronary plaques, OCT has been applied to characterize neointima after stent implantation. 12 Indeed, several OCT studies revealed the development of lipid-laden neointima inside the stents, and OCT has become the modality of choice to study atherosclerotic change of neointima. 7,9,10 Background-Recent studies have reported development of neoatherosclerosis (NA) inside the stents several years after stent implantation. The aim of this study was to determine the predictors for NA using optical coherence tomography. Methods and Results-From a total of 1080 patients who underwent optical coherence tomography, we identified 179 stents in 151 patients in which the mean neointimal thickness was >100 µm. The presence of lipid-laden neointima or calcification inside the stents was defined as NA in the present study. Patient characteristics, stent type, and time since stent implantation (stent age) were compared between stents with or without NA.

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“…† Furthermore, it appears that this increase in risk is present with even mild reduction in kidney function. 174,177,178 In high-risk populations, most but not all studies have suggested that decreased GFR is an independent risk factor for outcomes. This is true in the elderly, in whom even mild reductions of kidney function are associated with worse outcomes, 137 in studies of subjects with hypertension, 4 in studies of populations with a higher than normal prevalence of diabetes, 165 and among older patients undergoing general surgery.…”

Section: Reduced Gfrmentioning

confidence: 99%