Graafian follicle development throughout the reproductive cycle in the guinea pig, with especial reference to changes during oestrus (sexual receptivity)

Myers, Hugh I.; Young, William C.; Dempsey, Edward W.

doi:10.1002/ar.1090650404

Cited by 75 publications

(26 citation statements)

References 9 publications

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“…We found the number of follicles which develop beyond the primordial stage in the guinea pig ovary to be 100-280 regardless of the day of estrous cycle, thereby confirming previous reports (Myers et al, 1936;Dempsey et al, 1937;Schmidt, 1942;Labhsetwar and Diamond, 1970;Peddie, 1980 a, b;Garris and Foreman, 1984). Although the actual numbers of follicles varied considerably between individual ovaries, changes in the percentage distribution of follicular size were consistent in ovaries throughout cycle days 10-14.…”

supporting

confidence: 89%

Quantitative Determination of Follicle Size Distribution in the Guinea Pig Ovary after Hemicastration and PMSG Treatment.

Fujimori¹,

Nakamura

Tonetta

et al. 1989

Endocrinol Japon

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supporting

confidence: 89%

Quantitative Determination of Follicle Size Distribution in the Guinea Pig Ovary after Hemicastration and PMSG Treatment.

Fujimori¹,

Nakamura

Tonetta

et al. 1989

Endocrinol Japon

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“…These sections were analyzed for the number and size (mean of two largest diameters measured at right angles) of follicles large than 200 µm in diameter (this excludes small preantral follicles); follicle measurements were made without regard to the healthy or atretic status [2] but the follicles that contained a visible oocyte nucleus and some granulosa cells were included in the counts. A follicle large than 500 µm in size denotes a large antral follicle [17][18][19].…”

Section: Ovarian Histologymentioning

confidence: 99%

Ovarian Localization of Immunoglobulin G and Inhibin .ALPHA.-Subunit in Guinea Pigs after Passive Immunization against the Inhibin .ALPHA.-Subunit.

Shi

Mochida

Сузукі

et al. 2000

Journal of Reproduction and Development

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Abstract. The experiment was conducted to elucidate ovarian localization of immunoglobulin G (Ig G) and inhibin α-subunit and follicular development in guinea pigs after passive immunization against the inhibin α-subunit. Estrus was synchronized in laboratory guinea pigs by implanting progesterone containing-tubes. After removal of the progesterone implants, the guinea pigs were injected i.v. with 1.0 ml inhibin antiserum or normal goat serum (NGS). The results showed that Ig G mainly entered the follicular fluid of antral follicles, indicating that possibly inhibin antibodies could be a local regulator affecting follicular development in guinea pigs. The results also showed that passive immunization against inhibin increased the number of follicles and plasma concentrations of estradiol before ovulation, but did not change the plasma concentrations of follicle-stimulating hormone (FSH) or the numbers of follicles stained with inhibin antiserum. The present study first reports that the distribution of Ig G after injections of inhibin antiserum and confirms our previous hypothesis that only dominant follicles could be stained for inhibin α-subunit. The results also imply that only one injection of inhibin antiserum could not increase the ovulation rate in guinea pigs.

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“…In some mammals, however, the morphology of follicular and oocyte developmental processes has been correlated with events in the estrous cycle. For instance, Myers et al (1936) made a careful histological examination of follicles in ovaries removed at known times of the 16-17 day estrous cycle of the guinea pig. They reported that soon after estrus many multilaminar primary (nonvesicular) follicles had begun to form an antrum thus becoming a secondary or vesicular follicle, and that from these only two or three follicles in each ovary complete their development and ovulate at the next estrus; the remainder becoming atretic at various stages of their growth.…”

Section: Introductionmentioning

confidence: 99%

Studies on the Human Oocyte and Its Follicle

Hertig

Adams

1967

The Journal of Cell Biology

230

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Oocytes in primordial ("resting") follicles in adult human ovaries contain a complex paranuclear structure identified by light microscopists as Balbiani's vitelline body. By electron microscopy this structure is composed of a mass of mitochondria with associated endoplasmic reticulum, multiple compound aggregates which form a ring around the cytocentrum, and a single stack or coil of annulate lamellae either attached to the nuclear membrane or free in the cytoplasm. The compound aggregates contain vacuoles and finely divided electronopaque material Evidence is presented for the probable transport of this material between the oocyte and its environment. The cytocentrum contains a central aggregate of amorphous electron-opaque deposits which appear to become periodically aligned on fine fibrils to form the long coarse fibers at the periphery of the cytocentrum. The apparent prevalence of annulate lamellae attached or adjacent to the nuclear membrane of oocytes in ovaries removed during the mid-follicular (estrogenic) phase of the cycle indicates the need for further study of a possible hormonal influence on the resting oocyte. By light microscopy phosphatases were not found within the oocyte, but adenosine-monophosphatase activity is present in the cortical cells surrounding primordial follicles, and also at the periphery of each primitive follicle cell, most prominently at the oocyte side. Glucose-6-phosphate dehydrogenase activity is present within the oocyte cytoplasm.

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Graafian follicle development throughout the reproductive cycle in the guinea pig, with especial reference to changes during oestrus (sexual receptivity)

Cited by 75 publications

References 9 publications

Quantitative Determination of Follicle Size Distribution in the Guinea Pig Ovary after Hemicastration and PMSG Treatment.

Quantitative Determination of Follicle Size Distribution in the Guinea Pig Ovary after Hemicastration and PMSG Treatment.

Ovarian Localization of Immunoglobulin G and Inhibin .ALPHA.-Subunit in Guinea Pigs after Passive Immunization against the Inhibin .ALPHA.-Subunit.

Studies on the Human Oocyte and Its Follicle

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