The article examines the specific features of Swiss regional strategy. The influence of federalism characterized by certain symmetry with equal status of regions in relations with central government is analyzed. The author uses system, structural and functional methods, comparative and historical analysis in the study of power distribution between center and regions and its particular features at all levels of power in Switzerland. The Federal Government and cantons promote the application of ideas and projects for strengthening regional economies in line with the needs of each region. Special attention is paid to the formation process of regional strategy taking into account power decentralization, principle of direct democracy and challenges of globalization. The specific territorial structure of Confederation and the governance system “from bottom to top”, multinational society, broad autonomy of cantons, its niche orientation which requires inter-cantonal cooperation – all these factors determine the main guidelines of Swiss regional policy. Scientific novelty lies in determination of these factors. The New regional policy (NRP) adopted in 2008 focuses primarily on mountain, rural and border regions and has intentionally been designed to be flexible. Its second funding period was devoted to regional innovation and structural transformation of the tourism industry. The detailed investigation realized by the author allows to estimate the formation stages of Swiss regional policy, its strategic goals, economic effects and the current state, so it may be useful for regional development in Russia including implementation of innovations in regions.