Good clinical practice in orthokeratology

Cho, Pauline; Cheung, Sin Wan; Mountford, John; White, Priscilla

doi:10.1016/j.clae.2007.07.003

Cited by 41 publications

(33 citation statements)

References 20 publications

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“…This is consistent with the concept that myopia OK lenses induce apical corneal epithelial thinning. 1,5,8,[15][16][17] After one night of OK lens wear, the maximum thinning magnitudes of central epithelium were 7% and 6% at the horizontal and vertical meridians, respectively. The magnitude reached 14% at the vertical meridian and 16% at the horizontal meridian after seven nights of wear.…”

Section: Discussionmentioning

confidence: 99%

“…[3][4][5] With the development of higher gas-permeable lens materials, overnight OK lens has come into greater use as a treatment modality to correct refractive error. [6][7][8] Previous studies have reported the time course of refractive and topographic thickness changes of the cornea and its sublayers in myopia OK lens wearers. [9][10][11] In an early study, Swarbrick et al, using a modified optical pachymeter, found central epithelial thinning and midperipheral corneal thickening after reverse-geometry lens wear.…”

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confidence: 99%

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Vertical and Horizontal Thickness Profiles of the Corneal Epithelium and Bowman's Layer after Orthokeratology

Liang

Shen

Jiang

et al. 2013

Invest. Ophthalmol. Vis. Sci.

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PURPOSE. To investigate thickness profile changes of the corneal epithelium and Bowman's layer at the vertical and horizontal meridians with overnight myopia orthokeratology (OK) lenses.METHODS. Twenty subjects (age range: 19-33 years) wore reverse-geometry rigid gas-permeable OK lenses in both eyes for 30 days. Before lens wear and after 1, 7, and 30 days of overnight lens wear, evaluation of lens fitting, visual acuity examination, corneal topography, and ultra-high resolution optical coherence tomography (UHR-OCT) were performed. The central, midperipheral, and peripheral cornea were imaged in both the horizontal and vertical meridians. Custom software was produced to acquire the thickness profiles of the epithelium and Bowman's layer. RESULTS.Unaided visual acuity and refraction were improved significantly after OK lens wear. The central corneal epithelium thinned in the horizontal and vertical meridians after one night of lens wear (P < 0.05). In the horizontal meridian, the epithelium thickened at the temporal and nasal midperipheries (P < 0.05), while the superior midperipheral epithelium thinned in the vertical meridian. There were no changes in the thickness profile of Bowman's layer during the study period.CONCLUSIONS. Overnight wear of OK lenses caused the central corneal epithelium to thin in both the vertical and horizontal meridians, while the midperipheral nasal and temporal epithelium became thicker and the superior midperipheral epithelium became thinner. The thickness of the central or midperipheral Bowman's layer in either meridian did not change. Improved vision acuity after overnight OK lens wear can be attributed to changes in the corneal epithelium and not Bowman's layer. (Invest Ophthalmol Vis Sci. 2013;54:691-696) DOI:10.1167/iovs.12-10263 O rthokeratology (OK) is used to temporarily reduce the refractive error in myopic patients by the programmed application of specially designed rigid contact lenses.1,2 The improvement of uncorrected visual acuity and reduction in myopia are attained by flattening and thinning of the central cornea. OK lenses for myopia provide reliable refractive correction for up to À4.5 diopters (D) on lens removal. [3][4][5] With the development of higher gas-permeable lens materials, overnight OK lens has come into greater use as a treatment modality to correct refractive error. [6][7][8] Previous studies have reported the time course of refractive and topographic thickness changes of the cornea and its sublayers in myopia OK lens wearers. [9][10][11] In an early study, Swarbrick et al., using a modified optical pachymeter, found central epithelial thinning and midperipheral corneal thickening after reverse-geometry lens wear.9 Albarbi et al. obtained similar results using an overnight OK lens-wearing modality. 10Wang et al. used optical coherence tomography (OCT) to measure the topographic thickness of the cornea and epithelium after one night of OK lens wear. 11 However, all of these studies were focused on thickness changes of the total cornea and the epitheliu...

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Vertical and Horizontal Thickness Profiles of the Corneal Epithelium and Bowman's Layer after Orthokeratology

Liang

Shen

Jiang

et al. 2013

Invest. Ophthalmol. Vis. Sci.

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“…Orthokeratology (OK) uses specially designed rigid contact lenses to reshape the cornea in order to temporarily reduce or eliminate refractive error [21,22]. Modern OK using sophisticated contact lenses with a reverse-geometry design can provide faster, larger, and more predictable refractive changes than OK lenses used in the original method introduced in the early 1960s [23].…”

Section: Introductionmentioning

confidence: 99%

Overnight orthokeratology is comparable with atropine in controlling myopia

Lin

Tsai

et al. 2014

BMC Ophthalmol

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BackgroundMany efforts have been invested in slowing progression of myopia. Among the methods, atropine administration and orthokeratology (OK) are most widely used. This study analyzed the efficacy of atropine and OK lens in controlling myopia progression and elongation of axial length.MethodsThis retrospective study included 105 patients (210 eyes) who wore OK lenses and 105 patients (210 eyes) who applied 0.125% atropine every night during the 3 following period. Student t-test, linear regression analysis, repeated measure ANOVA, and Pearson’s correlation coefficient were used for statistical analysis.ResultsThe change in axial length per year was 0.28 ± 0.08 mm, 0.30 ± 0.09 mm, and 0.27 ± 0.10 mm in the OK lens group, and 0.38 ± 0.09 mm, 0.37 ± 0.12 mm, and 0.36 ± 0.08 mm in the atropine group for years 1, 2, and 3, respectively. Linear regression analysis revealed an increase in myopia of 0.28 D and 0.34 D per year, and an increase in axial length of 0.28 mm and 0.37 mm per year in the OK lens and atropine groups, respectively. Repeated measure ANOVA showed significant differences in myopia (p = 0.001) and axial length (p < 0.001) between the atropine and OK lens groups; in astigmatism, there was no significant difference in these parameters (p = 0.320). Comparison of increases in axial length in relation to baseline myopia showed significant correlations both in the OK lens group (Pearson’s correlation coefficient, r = 0.259; p < 0.001) and atropine group (r = 0.169; p = 0.014). High myopia patients benefited more from both OK lenses and atropine than did low myopia patients. The correlation of baseline myopia and myopia progression was stronger in the OK lens group then in the atropine group.ConclusionsOK lens is a useful method for controlling myopia progression even in high myopia patients.

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“…(Hiraoka et al 2008) Despite scientific conjecture on visual quality, patient satisfaction with OK treatment is high, (Hiraoka et al 2009 and they are demonstrated to be safe for children and adults to wear when appropriate fitting and patient education is undertaken. (Young et al 2004, Mika et al 2007, Cho et al 2008, Van Meter et al 2008, Walline et al 2009 …”

Section: Orthokeratologymentioning

confidence: 99%

“…All had myopia between 0.75 and 4.50D, with no more than 1.50D of with-the-rule astigmatism or 0.75D of against-the-rule astigmatism (Mountford 1997, Cho et al 2008 They achieved best-corrected acuity in soft contact lenses (SCL) of 6/6 in each eye before OK treatment, had no history of a previously treated BV disorder or vision training, no contraindications to contact lens wear including ocular surface disease, no ocular pathology, strabismus, amblyopia or other vision problems aside from refractive ametropia, and no previous rigid contact lens wear. The study was BIFR and BOFR were determined using the jump method with a prism bar in free space.…”

Section: Participants and Inclusion Criteriamentioning

confidence: 99%

Binocular Visual Function in Orthokeratology Contact Lens Wear for Myopia

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Good clinical practice in orthokeratology

Cited by 41 publications

References 20 publications

Vertical and Horizontal Thickness Profiles of the Corneal Epithelium and Bowman's Layer after Orthokeratology

Vertical and Horizontal Thickness Profiles of the Corneal Epithelium and Bowman's Layer after Orthokeratology

Overnight orthokeratology is comparable with atropine in controlling myopia

Binocular Visual Function in Orthokeratology Contact Lens Wear for Myopia

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