Gonococcal pharyngeal infections. Report of 110 cases.

Bro-Jorgensen, A; Jensen, T

doi:10.1136/sti.49.6.491

Cited by 59 publications

(41 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As a result of our favourable situation, we had no problems in treating the patients with genital infections in whom the cure rate was 98 per cent. However, as reported by other authors (Bro-J0rgensen and Jensen, 1973;Odegaard and Gundersen, 1973;Stolz and Schuller, 1974), standard treatment was unsuccessful in pharyngeal infections in which the failure rate was 61 per cent. Promising results were obtained with high doses of penicillin intramuscularly for 2 days.…”

Section: Discussionmentioning

confidence: 64%

Gonorrhoea in 1972. A 1-year study of patients attending the VD Unit in Uppsala.

Wallin¹

1975

Sexually Transmitted Infections

View full text Add to dashboard Cite

During 1972 all patients visiting the Venereal Disease Clinic of the University Hospital in Uppsala were subjected to careful and extensive interrogation, and the information so obtained was adapted for computer reading, as were the results of clinical examination and microbiological tests. The aim of this programme was not only to evaluate the adequacy of current therapy and epidemiological efforts, but also to illnte problems concerned with information and attitudes. The diagnosis of gonorrhoea was made if either a smear or a culture was positive for gonococci. Smears were considered positive if there was a collection of monomorphic diplococci within a neutrophilic granulocyte stained with methylene blue. Specimens from men were taken from the urethra and in a few cases also from the rectum, and in women from the urethra, cervix, and rectum. The material was transported in Stuart's medium to the laboratory and the culture set up within a few hours. Tonsillar swabs were taken from patients with an untreated gonococcal infection and from patients named as contacts. These were also sent to the laboratory in Stuart's medium and positive cultures from this site were confirmed with fermentation reactions. Methods PATIENTS TREATMENT SCHEDULES FOR GONORRHOEAThe standard treatment was a total of 2 g. ampicillin taken orally as two doses of 1 g. with a 5-hr interval. This treatment was given to 84 per cent. of the patients and the others were treated with either doxycycline, 300 mg. in a single oral dose, or 1 m.u. aqueous benzyl penicillin plus 1 2 m.u. aqueous procaine penicillin in a single injection. The efficacy of the therapy was checked by culture for N. gonorrhoeae of specimens taken one and two weeks after treatment.

show abstract

Section: Discussionmentioning

confidence: 64%

Gonorrhoea in 1972. A 1-year study of patients attending the VD Unit in Uppsala.

Wallin¹

1975

Sexually Transmitted Infections

View full text Add to dashboard Cite

show abstract

“…Only three of the 50 isolates of a-haemolytic streptococci were without inhibitory activity to any of the 20 isolates of N gonorrhoeae tested; a further nine inhibited only one isolate of N gonorrhoeae (fig 2). On the other hand, 18 (36%) 16 (80Gb) isolates of N gonorrhoeae, even though only one isolate of streptococci inhibited all 20 isolates of N gonorrhoeae.…”

Section: Bacterial Strainsmentioning

confidence: 99%

Bacterial interference of Neisseria gonorrhoeae by alpha-haemolytic streptococci.

McBride¹,

Duncan²,

Knox³

1980

Sexually Transmitted Infections

View full text Add to dashboard Cite

SUMMARY Fifty pharyngeal isolates of a-haemolytic streptococci were tested against 20 cervical isolates of Neisseria gonorrhoeae for bacterial interference in vitro using the lawn-spotting method. Forty-seven (94Vo) isolates of streptococci showed inhibitory activity toward N gonorrhoeae, although nine of these were inhibitory to only one isolate of Ngonorrhoeae. Isolates of N gonorrhoeae varied widely in their sensitivity to streptococci; the most sensitive were inhibited by 40 isolates of streptococci and the least sensitive by only 14 isolates. Species of Streptococcus found to inhibit growth of N gonorrhoeae were S mitis, S MG intermedius, S sanguis II, S mutans, and S morbillorum.

show abstract

“…Gonococcal infections of the pharynx are generally asymptomatic [151][152][153]. Several recent studies have identified a high prevalence of asymptomatic gonococcal infections of the pharynx in specific populations, such as MSM, STD clinic patients, and HIV-positive patients.…”

Section: Gonococcal Infections Of the Pharynxmentioning

confidence: 98%

Update on the Management of Gonorrhea in Adults in the United States

Newman

Moran

Workowski

2007

Clinical Infectious Diseases

171

110

View full text Add to dashboard Cite

Gonorrhea, the second most commonly reported notifiable disease, is an important cause of cervicitis, urethritis, and pelvic inflammatory disease. The selection of appropriate therapy for gonorrhea (i.e., safe, highly effective, single dose, and affordable) is complicated by the ability of Neisseria gonorrhoeae to develop resistance to antimicrobial therapies. This article reviews the key questions and data that informed the 2006 gonorrhea treatment recommendations of the Centers for Disease Control and Prevention. Key areas addressed include the criteria used to select effective treatment for gonorrhea, the level of antimicrobial resistance at which changing treatment regimens is recommended, the epidemiology of resistance, and the use of quinolones, cephalosporins, and other classes of antimicrobials for the treatment of uncomplicated gonorrhea.

show abstract

Gonococcal pharyngeal infections. Report of 110 cases.

Cited by 59 publications

References 9 publications

Gonorrhoea in 1972. A 1-year study of patients attending the VD Unit in Uppsala.

Gonorrhoea in 1972. A 1-year study of patients attending the VD Unit in Uppsala.

Bacterial interference of Neisseria gonorrhoeae by alpha-haemolytic streptococci.

Update on the Management of Gonorrhea in Adults in the United States

Contact Info

Product

Resources

About