Goniodysgenesis and Hereditary Juvenile Glaucoma

Jerndal, Tord

doi:10.1111/j.1755-3768.1970.tb03759.x

Cited by 24 publications

(12 citation statements)

References 90 publications

(56 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The classification of simple glaucoma is permitted only when the irido-corneal angles are open and free from a) maldevelopmental signs at the angle and b) secondary changes such as exfoliation phenomenon, excessive pigmentation, and postuveitic synechiae. According to the criteria described by Jerndal (1970) by using a meticulous gonioscopy with high magnification and narrow slit, angle maldevelopment (goniodysgenesis) was found in 185 eyes, and these eyes were therefore classified as late congenital glaucoma. With a less accurate gonioscopic technique these cases would probably have been classified as simple glaucoma.…”

Section: T Jerndal and M Lundstriimmentioning

confidence: 99%

330 Trabeculectomies — A Follow‐up Study Through ½‐3 Years

Jerndal

Lundström

1977

Acta Ophthalmologica

View full text Add to dashboard Cite

In 1967 a new microsurgical procedure for glaucoma known as trabeculectomy was introduced. This method is reported to have few early complications and a good pressure-reducing effect. Our material presents the results of 330 consecutive trabeculectomies with a follow-up period of 1/2-3 years. The following items are discussed: IOP, visual acuity, visual fields, surgical complications, and need of re-operation and medical postoperative therapy. We conclude that trabeculectomy is a safe and efficient antiglaucoma operation, recommended as an attractive alternative to heavy medication.

show abstract

Section: T Jerndal and M Lundstriimmentioning

confidence: 99%

330 Trabeculectomies — A Follow‐up Study Through ½‐3 Years

Jerndal

Lundström

1977

Acta Ophthalmologica

View full text Add to dashboard Cite

show abstract

“…Some studies suggested that juvenile glaucoma may need primary surgical treatment 24,25. However, since JOAG has also been postulated to be a subset of adult POAG with an earlier age of onset, it may be possible to give these patients a trial of medical therapy 26.…”

Section: Discussionmentioning

confidence: 99%

Anisohypermetropia as a sign of unilateral glaucoma in the pediatric population

Tan

Teh

et al. 2017

IMCRJ

View full text Add to dashboard Cite

Childhood glaucoma poses a diagnostic and therapeutic challenge to ophthalmologists. Difficulty in examination and limitations on ability to perform structural and functional testing of optic nerve make diagnosis and verification of glaucoma control difficult in children. It is well known that an excessive loss of hyperopia is a useful sign in alerting the examining ophthalmologist to the possible diagnosis of glaucoma. We present an interesting case of juvenile onset glaucoma presenting with anisohypermetropic amblyopia in one eye and normal vision in the fellow eye that has glaucoma. It is an unusual case as the left eye with abnormal vision from hypermetropic amblyopia, though by itself requiring treatment, was a red herring for a potentially blinding condition in the fellow eye with normal vision and lower and less amblyogenic hyperopia on examination. We believe that glaucomatous enlargement of the right eye resulted in significant loss of hyperopia in that eye and in turn contributed to anisohypermetropic amblyopia in the left eye. To the best of our knowledge, this is the first reported case of juvenile onset glaucoma presenting with anisohypermetropic amblyopia in one eye and normal vision in the fellow eye that has glaucoma.

show abstract

“…What was interesting was that greater bilaterality was seen among younger patients, whereas those with a unilateral optic neuropathy in our study were older in age. The pathogenesis of raised IOP in JOAG is ascribed to a goniodysgenesis involving lack of maturity of trabecular meshwork and thickened trabecular beams 17,18 . It is reported that developmental abnormalities of the angle tend to be less obvious as the age of onset increases 19 .…”

Section: Discussionmentioning

confidence: 99%

“…The pathogenesis of raised IOP in JOAG is ascribed to a goniodysgenesis involving lack of maturity of trabecular meshwork and thickened trabecular beams. 17,18 It is reported that developmental abnormalities of the angle tend to be less obvious as the age of onset increases. 19 It is probable that those presenting at a later age may have less severe developmental anomalies of the trabecular meshwork and hence tend to have only one eye involved.…”

Section: Discussionmentioning

confidence: 99%