Gonadotropin secretory capacity in a patient with Sheehan’s syndrome with successful pregnancies

Perinatal Management and Outcomes of Pregnancy Following Sheehan Syndrome: A Case Report and Literature Review

“…When and how to terminate the pregnancies following Sheehan syndrome has no consensus. According to previous case reports, the delivery gestational age ranged from 32 weeks to 41 weeks in the 22 pregnancies, 14/22 cases (63.64%) delivered full-term 6,9–19,22,24,26–29 . In the 27 pregnancies which described the delivery mode, 15/27 (55.56%) pregnancies had a vaginal delivery 5,8,10,12,13,15,17,18,24,25,27 and 12/27 (44.44%) terminated by cesarean section 6,7,9,11,14,16,19,25,28,29 .…”

“…According to previous case reports, the delivery gestational age ranged from 32 weeks to 41 weeks in the 22 pregnancies, 14/22 cases (63.64%) delivered full-term. 6,[9][10][11][12][13][14][15][16][17][18][19]22,24,[26][27][28][29] In the 27 pregnancies which described the delivery mode, 15/27 (55.56%) pregnancies had a vaginal delivery 5,8,10,12,13,15,17,18,24,25,27 and 12/27 (44.44%) terminated by cesarean section. 6,7,9,11,14,16,19,25,28,29 Patients with panhypopituitarism or preexisting isolated central DI can get spontaneous delivery.…”

“…To the best of our knowledge, there were 24 papers 5–28 which we can get the full text and one conference abstract 29 published in English after 1950 related to pregnancy following Sheehan syndrome in Pubmed, Medline, Embase, and Google scholar. In the 25 papers and our case, there have been 27 patients with Sheehan syndrome and 32 pregnancies.…”

“…ACTH: Adrenocorticotropic hormone; DI: Diabetes insipidus; FSH: Follicle stimulating hormone; GH: Growth hormone; HCG: Human chorionic gonadotropin; HMG: Human menopausal gonadotropin; IUI: Intrauterine insemination; IVF-ET: In vitro fertilization and embryo transfer; LH: Luteinizing hormone; NS: Not specified (There are some missing data in those article) PRL: Prolactin; TSH: Thyroid-stimulating hormone.∗Jackson IM, et al 8 . (1969) reported two patients.†Moreira AC, et al 15 . (1984) reported four pregnancies of one patient.‡Briet JW, et al 18 (1998) reported two pregnancies of one patient.§Laway BA, et al 25 (2013) reported two pregnancies of one patient.…”

“…CHM: Complete hydatidiform mole; CS: Cesarean section; DCDA: Dichorionic diamniotic; DI: Diabetes insipidus; GDM: Gestational diabetes mellitus; IUGR: Intrauterine growth restriction; MCDA: Monochorionic diamniotic; NS: Not specified (There are some missing data in those articles); PD: Preterm delivery; PE: Pre-eclampsia; PPH: Postpartum hemorrhage; PRL: Prolactin; TSH: Thyroid-stimulating hormone; VD: Vaginal delivery.∗Jackson IM, et al 8 . (1969) reported two patients.†Moreira AC, et al 15 . (1984) reported four pregnancies of one patient.‡Briet JW, et al 18 (1998) reported two pregnancies of one patient.§Laway BA, et al 25 (2013) reported two pregnancies of one patient.…”