Gold–Thiol Self‐Assembled Monolayers

Chechik, Victor; Stirling, Charles J. M.

doi:10.1002/9780470682531.pat0220

Cited by 3 publications

(1 citation statement)

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“…These properties can be used for specific and non-specific binding of biomolecules and nanoparticles and, therefore, can serve as useful templates for nano- and micro-fabrication. The first systematic study of thiol chemicals was reported by Zisman and co-authors [ 1 ], and has since been investigated by many researchers, including a detailed review by Chechik et al [ 2 ]. SAMs can be defined as "molecular assemblies that are formed spontaneously be the immersion of an appropriate substrate into a solution of an active surfactant in an organic solvent" [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

AFM-assisted fabrication of thiol SAM pattern with alternating quantified surface potential

Moores

Simons

et al. 2011

Nanoscale Res Lett

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Thiol self-assembled monolayers (SAMs) are widely used in many nano- and bio-technology applications. We report a new approach to create and characterize a thiol SAMs micropattern with alternating charges on a flat gold-coated substrate using atomic force microscopy (AFM) and Kelvin probe force microscopy (KPFM). We produced SAMs-patterns made of alternating positively charged, negatively charged, and hydrophobic-terminated thiols by an automated AFM-assisted manipulation, or nanografting. We show that these thiol patterns possess only small topographical differences as revealed by AFM, and distinguished differences in surface potential (20-50 mV), revealed by KPFM. The pattern can be helpful in the development of biosensor technologies, specifically for selective binding of biomolecules based on charge and hydrophobicity, and serve as a model for creating surfaces with quantified alternating surface potential distribution.

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Section: Introductionmentioning

confidence: 99%