Gold nanorods crosslinking PNIPAM hydrogels via dynamic Au-thiolate interaction with stretchable, adhesive, self-healing, and photothermal properties

Lin, Shuo; Jiang, Sirui; Zhang, Yuchen; Dai, Zheng-Wei; Dai, Yu; Xia, Fan; Zhang, Xiaojin

doi:10.1007/s13404-021-00293-6

Cited by 9 publications

(3 citation statements)

References 33 publications

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“…S2 ). The polymer is temperature-sensitive [ 31 ] and might coordinate with metal ions via the interaction between metal ions and disulfides [ 32 ].…”

Section: Resultsmentioning

confidence: 99%

CuS-PNIPAm nanoparticles with the ability to initiatively capture bacteria for photothermal treatment of infected skin

Wang

Hou

Wang

et al. 2022

Regenerative Biomaterials

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Copper sulfide nanoparticles (CuS NPs) have shown great potential in various application fields, especially in biomedical engineering fields. CuS NPs, with the ability to actively capture and kill bacteria and without the worry of biocompatibility, will greatly expand their applications. Herein, a four-arm star thermo-sensitive polyisopropylacrylamide (4sPNIPAm) was used to modify CuS NPs (CuS-PNIPAm NPs). The obtained nanoparticles displayed the controlled release of copper ions and higher photothermal conversion ability in comparison with contrast materials CuS-PEG NPs and CuS NPs. Aggregation of CuS-PNIPAm NPs at above 34 °C resulted in capturing bacteria by forming the aggregates of nanoparticles-bacteria. Both S. aureus and E. coli co-cultured with CuS-PNIPAm NPs were completely killed upon NIR irradiation in minutes. Furthermore, CuS-PNIPAm NPs were verified to be a photothermal agent without toxic effect. In in vivo experiment, the nanoparticles effectively killed the bacteria in the wound and accelerated the process of wound repairment. Overall, photothermal treatment by CuS-PNIPAm NPs demonstrates the ability to actively capture and kill bacteria, and has a potential in the treatment of infected skin and the regeneration of skin tissues. The therapy will exert a far-reaching impact on the regeneration of stubborn chronic wounds.

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“…S2 ). The polymer is temperature-sensitive [ 31 ] and might coordinate with metal ions via the interaction between metal ions and disulfides [ 32 ].…”

Section: Resultsmentioning

confidence: 99%

CuS-PNIPAm nanoparticles with the ability to initiatively capture bacteria for photothermal treatment of infected skin

Wang

Hou

Wang

et al. 2022

Regenerative Biomaterials

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“…For the sake of avoiding the commonly used multistep surface modification method for synthesizing gold nanorod (AuNR) crosslinkers, Lin et al. [ 137 ] used N,N' ‐bis(acryloyl)cysteamine (BACA)‐modified AuNR as a crosslinking agent, and polymerized AuNR crosslinking poly( N ‐isopropylacrylamide) (PNIPAM) hydrogels through the interaction between dynamic Au‐thiolate and NIPAM. Before hydrogel formation, the reversible Au‐thiolate bonding was formed by directly mixing AuNR and BACA so that the AuNR crosslinker was conveniently prepared.…”

Section: Enhancing Toughness Via Improving Functionalities Of Crossli...mentioning

confidence: 99%

“…1D NC hydrogels Lu et al [ 135] PAAM-silica nanofiber 1400 -300 -Yu and Zhu [ 136] PAA-HAP nanowire --9330 -Lin et al [ 137] AuNR-PNIPAM 3400 -4.5 -2D NC hydrogels Pereira et al [ 139] PHEMA/GO 200 -1140 6500…”

Section: Physically Crosslinked Dn Hydrogelsmentioning

confidence: 99%

Recent Advances in Design Strategies of Tough Hydrogels

Zhang

Xiang

Yang

et al. 2022

Macromol. Rapid Commun.

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Hydrogels are a fascinating class of materials popular in numerous fields, including tissue engineering, drug delivery, soft robotics, and sensors, thanks to their 3D network porous structure containing a significant amount of water. However, traditional hydrogels exhibit poor mechanical strength, limiting their practical applications. Thus, many researchers have focused on the development of mechanically enhanced hydrogels. This review describes the design considerations for constructing tough hydrogels and some of the latest strategies in recent years. These tough hydrogels have an up‐and‐coming prospect and bring great hope to the fields of biomedicine and others. Nonetheless, it is still no small challenge to realize hydrogel materials that are tough, multifunctional, intelligent, and with zero defects.

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Thiol-functionalized chitosan poly(protic ionic liquids) hydrogel selectively anchors gold nanoparticles for aqueous catalysis

et al. 2023

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Gold nanorods crosslinking PNIPAM hydrogels via dynamic Au-thiolate interaction with stretchable, adhesive, self-healing, and photothermal properties

Cited by 9 publications

References 33 publications

CuS-PNIPAm nanoparticles with the ability to initiatively capture bacteria for photothermal treatment of infected skin

CuS-PNIPAm nanoparticles with the ability to initiatively capture bacteria for photothermal treatment of infected skin

Recent Advances in Design Strategies of Tough Hydrogels

Thiol-functionalized chitosan poly(protic ionic liquids) hydrogel selectively anchors gold nanoparticles for aqueous catalysis

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