Gold Nanoparticles: Synthesis, Optical Properties, and Application

Ogarev, V. A.; Рудой, В. М.; Дементьева, О. В.

doi:10.1134/s2075113318010197

Cited by 36 publications

(18 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The optical properties of gold nanoparticles (AuNPs) depend on several factors including the size, shape, structure, and morphology of the nanoparticles [ 26 , 43 ]. The surface plasmon resonance (SPR) plays a vital role in light scattering and absorption, which causes different color detection of AuNPs.…”

Section: The Optical and Electrochemical Properties Of Metal Nanoparticlesmentioning

confidence: 99%

A Review on the Development of Gold and Silver Nanoparticles-Based Biosensor as a Detection Strategy of Emerging and Pathogenic RNA Virus

Ibrahim

Jamaluddin

Tan

et al. 2021

Sensors

View full text Add to dashboard Cite

The emergence of highly pathogenic and deadly human coronaviruses, namely SARS-CoV and MERS-CoV within the past two decades and currently SARS-CoV-2, have resulted in millions of human death across the world. In addition, other human viral diseases, such as mosquito borne-viral diseases and blood-borne viruses, also contribute to a higher risk of death in severe cases. To date, there is no specific drug or medicine available to cure these human viral diseases. Therefore, the early and rapid detection without compromising the test accuracy is required in order to provide a suitable treatment for the containment of the diseases. Recently, nanomaterials-based biosensors have attracted enormous interest due to their biological activities and unique sensing properties, which enable the detection of analytes such as nucleic acid (DNA or RNA), aptamers, and proteins in clinical samples. In addition, the advances of nanotechnologies also enable the development of miniaturized detection systems for point-of-care (POC) biosensors, which could be a new strategy for detecting human viral diseases. The detection of virus-specific genes by using single-stranded DNA (ssDNA) probes has become a particular interest due to their higher sensitivity and specificity compared to immunological methods based on antibody or antigen for early diagnosis of viral infection. Hence, this review has been developed to provide an overview of the current development of nanoparticles-based biosensors that target pathogenic RNA viruses, toward a robust and effective detection strategy of the existing or newly emerging human viral diseases such as SARS-CoV-2. This review emphasizes the nanoparticles-based biosensors developed using noble metals such as gold (Au) and silver (Ag) by virtue of their powerful characteristics as a signal amplifier or enhancer in the detection of nucleic acid. In addition, this review provides a broad knowledge with respect to several analytical methods involved in the development of nanoparticles-based biosensors for the detection of viral nucleic acid using both optical and electrochemical techniques.

show abstract

Section: The Optical and Electrochemical Properties Of Metal Nanoparticlesmentioning

confidence: 99%

A Review on the Development of Gold and Silver Nanoparticles-Based Biosensor as a Detection Strategy of Emerging and Pathogenic RNA Virus

Ibrahim

Jamaluddin

Tan

et al. 2021

Sensors

View full text Add to dashboard Cite

show abstract

“…Gold nanoparticles (AuNPs) are extensively used in a wide variety of areas, including electronics and nanotechnology [ 66 ]. It stems from their unique optical, physical, and chemical properties [ 67 ], as well as controllable synthesis [ 67 , 68 ]. The ability of AuNPs to be conjugated with many functionalizing agents, such as polymers, surfactants, ligands, dendrimers, drugs, DNA, RNA, proteins, peptides, and oligonucleotides, has led to their extended use in biomedical applications, disease diagnostics, and pharmaceuticals [ 69 – 71 ].…”

Section: Magnetic Solid Phase Extraction Used For the Separation Omentioning

confidence: 99%

Magnetic Solid Phase Extraction as a Promising Technique for Fast Separation of Metallic Nanoparticles and Their Ionic Species: A Review of Recent Advances

Hagarová

2020

Journal of Analytical Methods in Chemistry

View full text Add to dashboard Cite

The widespread use of silver nanoparticles (AgNPs) and gold nanoparticles (AuNPs) in a wide variety of industrial as well as medical sectors is indisputable. This leads to a new concern about their presence in various environmental compartments. Since their negative effect and potential toxicity impact have been confirmed, analytical chemists focus on the development of different procedures for their reliable detection, identification, characterization, and quantification, not only in homogenous and simple matrices but also in complex environmental matrices. However, nanoparticles and their ionic species can coexist and their toxicity may differ; therefore, novel analytical approaches are necessary to monitor not only the nanoparticles but also their ionic species. The aim of this article is to bring a review of recent works where magnetic solid-phase extraction (MSPE) procedures in connection with spectrometric methods were used for separation/preconcentration and quantification of (1) silver and gold ions in various environmental samples, (2) AgNPs and AuNPs in real water samples in the presence of various coexisting ions, and (3) both species (it means Ag ions and AgNPs; Au ions and AuNPs) in real water samples. The results presented herein show the great analytical potential of MSPE procedures in connection with spectrometric methods used in these fields and can be helpful in guiding analytical chemists who aim to work on this subject.

show abstract

“…In the wide class of nanomaterials, metal nanoparticles and in particular gold nanoparticles, are extensively used for biological applications, due to their size-related electronic [ 31 ], magnetic [ 32 ] and optical properties [ 33 ], as well as their straightforward functionalization.…”

Section: Introductionmentioning

confidence: 99%

Gold Nanoparticles Functionalized with Angiogenin for Wound Care Application

et al. 2021

View full text Add to dashboard Cite

In this work, we aimed to develop a hybrid theranostic nano-formulation based on gold nanoparticles (AuNP)—having a known anti-angiogenic character—and the angiogenin (ANG), in order to tune the angiogenesis-related phases involved in the multifaceted process of the wound healing. To this purpose, spherical were surface “decorated” with three variants of the protein, namely, the recombinant (rANG), the wild-type, physiologically present in the human plasma (wtANG) and a new mutant with a cysteine substitution of the serine at the residue 28 (S28CANG). The hybrid biointerface between AuNP and ANG was scrutinized by a multi-technique approach based on dynamic light scattering, spectroscopic (UV-visible, circular dichroism) and microscopic (atomic force and laser scanning confocal) techniques. The analyses of optical features of plasmonic gold nanoparticles allowed for discrimination of different adsorption modes—i.e.; predominant physisorption and/or chemisorption—triggered by the ANG primary sequence. Biophysical experiments with supported lipid bilayers (SLB), an artificial model of cell membrane, were performed by means of quartz crystal microbalance with dissipation monitoring acoustic sensing technique. Cellular experiments on human umbilical vein endothelial cells (HUVEC), in the absence or presence of copper—another co-player of angiogenesis—were carried out to assay the nanotoxicity of the hybrid protein-gold nanoassemblies as well as their effect on cell migration and tubulogenesis. Results pointed to the promising potential of these nanoplatforms, especially the new hybrid Au-S28CANG obtained with the covalent grafting of the mutant on the gold surface, for the modulation of angiogenesis processes in wound care.

show abstract

Gold Nanoparticles: Synthesis, Optical Properties, and Application

Cited by 36 publications

References 36 publications

A Review on the Development of Gold and Silver Nanoparticles-Based Biosensor as a Detection Strategy of Emerging and Pathogenic RNA Virus

A Review on the Development of Gold and Silver Nanoparticles-Based Biosensor as a Detection Strategy of Emerging and Pathogenic RNA Virus

Magnetic Solid Phase Extraction as a Promising Technique for Fast Separation of Metallic Nanoparticles and Their Ionic Species: A Review of Recent Advances

Gold Nanoparticles Functionalized with Angiogenin for Wound Care Application

Contact Info

Product

Resources

About