Gold nanoparticles stabilized by sulfonated imidazolium salt for the manufacture of modified electrodes in order to electrochemical detection of indomethacin

Monti, Gustavo A.; Velasco, Luis F. Berrio; Silbestri, Gustavo F.; Molina, Patricia G.; Moyano, Fernando

doi:10.1016/j.microc.2022.107992

Cited by 1 publication

(1 citation statement)

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“…12 Electrode modifiers such as alloys, metals, and metal oxides and the electrocatalytic enhancer like carbon-based materials, which increase the activity of the electrode material, are two important reasons that turned the focus of researchers toward the electroanalytical technique. 6 So far, electrode modifiers such as nitrogen-doped graphene oxide quantum dots (N-GOQDs), 13 Au NPs stabilized by 1-(3-sulfonatopropyl)imidazolium, 14 MoS 2 -coated SnO 2 −CNF, 15 spinel zinc ferrite nanoparticle (ZnFe 2 O 4 ), 16 chitosan-modified copper nanocubics, 17 and cadmium sulfide nanoparticles/multiwalled carbon nanotubes composite-modified gold electrode (CdSNPs/MWCNTS/ AuE) 18 were used to detect indomethacin. The current challenge is focused on optimizing the activation of GCEs to enhance their overall performance.…”

Section: Introductionmentioning

confidence: 99%

CoAl₂O₄-Anchored Carbon Nanofiber Electrodes for Indomethacin Sensing in Water and Biological Samples

Jayapaul,

Nixon,

Govindasamy

et al. 2024

ACS Appl. Nano Mater.

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Indomethacin (IDM) is commonly prescribed for headaches, fever, and articular disease as a nonselective nonsteroidal anti-inflammatory drug (NSAID), inhibiting prostaglandin synthesis to reduce fever, inflammation, and pain. However, its extensive use has resulted in water reservoir contamination from human and veterinary waste. Recognizing the urgent need for sustainable water contamination prevention and human health concerns, researchers have focused on indomethacin detection. In response, an innovative interdisciplinary platform, merging nanoscience and electrochemical engineering, was created. Detailed examination of the structural, crystallographic features and morphological insights of the electrode modifier was conducted. The nanocomposite's hierarchical arrangement, utilizing hybrid heterojunction and quantum confinement, enables synchronized indomethacin detection with a low limit of detection (LOD) of 39.3 nM. The resulting sensor demonstrates a wide linear range (0.001−264.02 μM), along with high sensitivity, selectivity, and stability. Expanding its utility, the sensor was successfully applied to water and human urine samples, showcasing its effectiveness in monitoring the proposed platform's consistency. This advancement shows promise in enhancing the sustainable detection of indomethacin in both environmental and biological settings.

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Section: Introductionmentioning

confidence: 99%

CoAl₂O₄-Anchored Carbon Nanofiber Electrodes for Indomethacin Sensing in Water and Biological Samples

Jayapaul,

Nixon,

Govindasamy

et al. 2024

ACS Appl. Nano Mater.

View full text Add to dashboard Cite

show abstract

Gold nanoparticles stabilized by sulfonated imidazolium salt for the manufacture of modified electrodes in order to electrochemical detection of indomethacin

Cited by 1 publication

References 35 publications

CoAl₂O₄-Anchored Carbon Nanofiber Electrodes for Indomethacin Sensing in Water and Biological Samples

CoAl₂O₄-Anchored Carbon Nanofiber Electrodes for Indomethacin Sensing in Water and Biological Samples

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Gold nanoparticles stabilized by sulfonated imidazolium salt for the manufacture of modified electrodes in order to electrochemical detection of indomethacin

Cited by 1 publication

References 35 publications

CoAl2O4-Anchored Carbon Nanofiber Electrodes for Indomethacin Sensing in Water and Biological Samples

CoAl2O4-Anchored Carbon Nanofiber Electrodes for Indomethacin Sensing in Water and Biological Samples

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CoAl₂O₄-Anchored Carbon Nanofiber Electrodes for Indomethacin Sensing in Water and Biological Samples

CoAl₂O₄-Anchored Carbon Nanofiber Electrodes for Indomethacin Sensing in Water and Biological Samples