Gold nanoparticles: an era in bionanotechnology

Kumar, Deepak; Saini, Nisha; Jain, Nitin; Sareen, Rashmi; Pandit, Vinay

doi:10.1517/17425247.2013.749854

Cited by 84 publications

(59 citation statements)

References 109 publications

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“…On the other hand, the effect of different geometries of gold nanoparticles was already summarized/studied systematically in various application, for targeted drug delivery and cancer treatment [32], therapeutical/phototermal effect [33], DNA detection [34], catalytic effect on CO oxidation [35] but to the best knowledge of the authors the effect of the various structures was not studied and correlated with their structural, photocatalytic properties and H 2 productivity.…”

Section: Introductionmentioning

confidence: 99%

Differently Shaped Au Nanoparticles: A Case Study on the Enhancement of the Photocatalytic Activity of Commercial TiO2

et al. 2014

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In the present work, the influence of a gold nanoparticle’s shape was investigated on the commercially available Evonik Aeroxide P25. By the variation of specific synthesis parameters, three differently shaped Au nanoparticles were synthetized and deposited on the surface of the chosen commercial titania. The nanoparticles and their composites’ morphological and structural details were evaluated, applying different techniques such as Diffuse Reflectance Spectroscopy (DRS), X-ray Diffraction (XRD), and Transmission Electron Microscopy (TEM). The influence of the Au nanoparticles’ shape was discussed by evaluating their photocatalytic efficiency on phenol and oxalic acid degradation and by investigating the H2 production efficacy of the selected composites. Major differences in their photocatalytic performance depending on the shape of the deposited noble metal were evidenced.

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Section: Introductionmentioning

confidence: 99%

Differently Shaped Au Nanoparticles: A Case Study on the Enhancement of the Photocatalytic Activity of Commercial TiO2

et al. 2014

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“…It is important to note that NPs were not used for encapsulating or conveying SCs on their surface due to their relatively small size, but for augmenting their circulation time, targeting cells towards specific tissues, improving SCs function in vivo [104], modifying cell behavior [105], delivering biomolecules and genes and for diagnostics and imaging methods [106].…”

Section: Nano/microparticles In Cell-based Therapiesmentioning

confidence: 99%

Heart regeneration after myocardial infarction using synthetic biomaterials

Pascual-Gil

Garbayo

Díaz-Herráez

et al. 2015

Journal of Controlled Release

121

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Abstract:Myocardial infarction causes almost 7.3 million deaths each year worldwide. However, current treatments are more palliative than curative. Presently, cell and protein therapies are considered the most promising alternative treatments. Clinical trials performed until now have demonstrated that these therapies are limited by protein short half-life and by low transplanted cell survival rate, prompting the development of novel cell and protein delivery systems able to overcome such limitations. In this review we discuss the advances made in the last 10 years in the emerging field of cardiac repair using biomaterial-based delivery systems with focus on the progress made on preclinical in vivo studies. Then, we focus in cardiac tissue engineering approaches, and how the incorporation of both cells and proteins together into biomaterials has opened new horizons in the myocardial infarction treatment. Finally, the ongoing challenges and the perspectives for future work in cardiac tissue engineering will also be discussed.

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“…In addition, they are able to protect systemic bioavailability, avoiding normal cells to be exposed to the drug toxicity [251][252][253]. The natural polymers are suitable materials to interact with the normal cells conferring to the DDS high biocompatibility [72]. The degradation compounds of biopolymers can be metabolized and rapidly cleared from the human body [27].…”

Section: Aunp Incorporation Into Polysaccharide-based Matrixmentioning

confidence: 99%

Supramolecular nanoscale assemblies for cancer diagnosis and therapy

Coelho

Pereira

Juzeniene

et al. 2015

Journal of Controlled Release

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Nanocarriers based on polymers, metals and lipids have been extensively developed for cancer therapy and diagnosis due to their ability to enhance drug accumulation in cancer cells and decrease undesired drug toxicity in healthy tissues. Overcoming multidrug resistance by designing proper drug nanocarriers will improve outcome of existing oncologic treatments such as chemotherapy or radiotherapy. In this article the relation between physicochemical properties and capacity of a nanosystem to deliver therapeutic agents into pathological sites is discussed. Most promising examples of drug delivery systems are reviewed, and, in particular, the design of a carbohydrate based matrix with entrapped gold nanoparticles is highlighted.

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Gold nanoparticles: an era in bionanotechnology

Abstract: Gold nanoparticles provide an admirable platform for the delivery of biomolecules and genes.

Cited by 84 publications

References 109 publications

Differently Shaped Au Nanoparticles: A Case Study on the Enhancement of the Photocatalytic Activity of Commercial TiO2

Differently Shaped Au Nanoparticles: A Case Study on the Enhancement of the Photocatalytic Activity of Commercial TiO2

Heart regeneration after myocardial infarction using synthetic biomaterials

Supramolecular nanoscale assemblies for cancer diagnosis and therapy

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