Gold Nanoparticle Transport in the Injured Kidneys with Elevated Renal Function Biomarkers
Xuhui Ning,
Yuncheng Zhong,
Qi Cai
et al.
Abstract:Renal function biomarkers such as serum blood urea nitrogen (BUN) and creatinine (Cr) serve as key indicators for guiding clinical decisions before administering kidney‐excreted small‐molecule agents. With engineered nanoparticles increasingly designed to be renally clearable to expedite their clinical translation, understanding the relationship between renal function biomarkers and nanoparticle transport in diseased kidneys becomes crucial to their biosafety in future clinical applications. In this study, ren… Show more
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