Gold nanoparticle film grown on quartz fiber and its application as a microsensor of nitric oxide

Dang, Xueping; Hu, Chengguo; Wang, Yingkai

doi:10.1016/j.snb.2011.07.045

Cited by 13 publications

(7 citation statements)

References 23 publications

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“…It may be attributed to the excellent conductivity and high electrocatalytic activity of AuNPs. It's worth mentioning that the anodic peak of AuNPs appears at about 0.8 V, which is close to that of NO (about 0.7 V) [117], the anodic peak current of NO would be interfered by AuNPs when voltammetry was engaged. So amperometry should be selected or NO should be detected via its electro-reduction for NO electrochemical sensor based on metal nanomaterials.…”

Section: Other Metal Nanomaterialsmentioning

confidence: 68%

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Nanomaterials-based electrochemical sensors for nitric oxide

Dang

Wang

et al. 2014

Microchim Acta

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Electrochemical sensing has been demonstrated to represent an efficient way to quantify nitric oxide (NO) in challenging physiological environments. A sensing interface based on nanomaterials opens up new opportunities and broader prospects for electrochemical NO sensors. This review (with 141 refs.) gives a general view of recent advances in the development of electrochemical sensors based on nanomaterials. It is subdivided into sections on (i) carbon derived nanomaterials (such as carbon nanotubes, graphenes, fullerenes), (ii) metal nanoparticles (including gold, platinum and other metallic nanoparticles); (iii) semiconductor metal oxide nanomaterials (including the oxides of titanium, aluminum, iron, and ruthenium); and finally (iv) nanocomposites (such as those formed from carbon nanomaterials with nanoparticles of gold, platinum, NiO or TiO 2 ). The various strategies are discussed, and the advances of using nanomaterials and the trends in NO sensor technology are outlooked in the final section.

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Section: Other Metal Nanomaterialsmentioning

confidence: 68%

“…After the modification by electropolymerized niacinamide and Nafion, the result NO microsensor exhibited high sensitivity and low-detection limit of 3.6 nmol·L −1 (Fig. 3 (right)), and was successfully employed in vivo detection of NO release from mice liver [117].…”

Section: Gold Nanomaterialsmentioning

confidence: 99%

Nanomaterials-based electrochemical sensors for nitric oxide

Dang

Wang

et al. 2014

Microchim Acta

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“…Figure A clearly indicates that the sensor has a remarkably larger current response for NO (36 μM) than that resulting from these interfering species (signal change less than 8.0%). Moreover, the small influences of nitrite (NO 2 – ) (NaNO 2 was used as the precursor to produce NO) at the same concentration (signal changes <10%) could be contributed from the negatively charged Nafion film acting as a barrier to repel the negatively charged nitrite due to the electrostatic repulsion while allowing the free penetration of neutral NO molecules (Figure B) . The satisfactory selectivity of the sensor matrix also came from high catalytic activity of N-G/FePc nanocomposite specifically toward NO oxidation.…”

Section: Resultsmentioning

confidence: 99%

Iron Phthalocyanine Decorated Nitrogen-Doped Graphene Biosensing Platform for Real-Time Detection of Nitric Oxide Released from Living Cells

Liao

Liu

et al. 2018

Anal. Chem.

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Nitric oxide (NO) is a transcellular messenger involved in many physiological and pathological processes, but the real-time detection of NO in biological systems is still challenging due to its rapid diffusion, low concentration, and short half-life. A novel electrochemical sensing platform based on iron phthalocyanine (FePc) functionalized nitrogen-doped graphene (N-G) nanocomposites was constructed to achieve in situ monitoring of NO released from living cells on the sensing layer. By taking advantage of the synergetic effect of N-G and FePc nanocomposites, the N-G/FePc sensor displays excellent electrocatalytic activity toward NO with a high sensitivity of 0.21 μA μM cm and a low detection limit of 180 nmol L. The following layer-by-layer assembly of poly-l-lysine (PLL) and Nafion further improved the capacity of resisting disturbance as well as the biocompatibility of the sensing interface. The flexible design of the ITO substrate based electrode provides a more controlled cellular biosensing system which could capture molecular signals immediately after NO released from human umbilical vein endothelial cells (HUVECs). The exhibited additional features of high sensitivity, rapid response, and ease of operation implies that the proposed N-G/FePc/Nafion/PLL ITO biosensor is a promising powerful platform in various complex biological systems.

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“…A gold nanoparticle (GNP) film based sensor grown on a quartz fiber by chemical liquid deposition exhibited high sensitivity and low‐detection limit of 3.6 nM ( S/N =3). Based on the catalytic effect of GNPs and polyniacinamide (PNA) toward the oxidation of NO, it was successfully employed in vivo detection of NO release from mice liver 83. Pt nanostructure with different shapes were prepared and served as catalysts to study the electrocatalytic reduction of both adsorbed and solution NO.…”

Section: Electrochemical Sensorsmentioning

confidence: 99%

Electrochemical Sensors for Nitric Oxide Detection in Biological Applications

Scafa

et al. 2014

Electroanalysis

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Nitric oxide (NO) plays an important role in physiological processes and it has been confirmed some human diseases are related to its biological function. Electrochemical sensors provide an efficient way to explore the NO function in biological processes. This review details different kinds of electrochemical sensors used for NO concentration detection between 2008 and 2013 together with their application in biological samples. Four commonly used electrodes and different assisted analysis membranes used for contributions towards the development of the novel sensors were summarized. Electrochemical sensors employed to measure NO concentration in a single cell, cell culture, tissue homogenate, organ, in vivo, human being, as well as in plant were also detailed. The trends of developing novel NO sensors were outlooked in the last part.

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Gold nanoparticle film grown on quartz fiber and its application as a microsensor of nitric oxide

Cited by 13 publications

References 23 publications

Nanomaterials-based electrochemical sensors for nitric oxide

Nanomaterials-based electrochemical sensors for nitric oxide

Iron Phthalocyanine Decorated Nitrogen-Doped Graphene Biosensing Platform for Real-Time Detection of Nitric Oxide Released from Living Cells

Electrochemical Sensors for Nitric Oxide Detection in Biological Applications

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