Gold‐Decorated Nanodiamonds: Powerful Multifunctional Materials for Sensing, Imaging, Diagnostics, and Therapy

Abstract

Gold-decorated nanodiamonds is an interesting multifunctional material that can find space in numerous applications in the biological field. The coupling and/or synergy of the properties of the individual components can offer interesting solutions in the field of optical labeling, imaging, molecule and drug delivery, and biosensing. This microreview describes the techniques used for the synthesis of these materials and in- [a]

Multimodal bioimaging using nanodiamond and gold hybrid nanoparticles

“…Additionally, it was found that combining Au with ND prevents Au nanostructure from degradation during photoacoustic imaging 28 . The same was observed with transmission electron microscopy (TEM) imaging 10 . Another synergy effect, the catalytic and sensor facilities are based on charge transfer process found only in the hybrid system 10 .…”

“…Combining Au with porous silica 2 , silicon 3 , iron oxides 4 , polymers 5 or other organic macromolecules, e.g. transition metals complexes 6 , different kinds of carbon nanomaterials 7 – 10 etc., have been described previously.…”

“…Among other currently used NP, hybrid gold-nanodiamond are novel multifunctional materials with tunable and tailored properties that have been considered for various biomedical applications. By combining nano-gold and nanodiamond, the synergetic properties of both materials can provide new options to combine optical labeling, imaging, sensing, and drug delivery as well as targeted treatment 10 . Both nanoscale gold and diamond materials have been demonstrated to be promising materials for use in biomedical researches and already in some medical applications.…”

“…The advantages of the synergy between gold and nanodiamond particles can be expected. However, the optical properties of the coupled Au and ND nanoparticles are not completely clear and predictable yet, leading to some contradictory results 10 . The ND-Au hybrid possess the plasmonic and photoacoustic properties of gold component 28 – 30 .…”

Covalent Functionalization of Nanodiamonds by Ruthenium Porphyrin, and Their Catalytic Activity in the Cyclopropanation Reaction of Olefins

“…DNDs have exceptional physiochemical properties and present a broad range of potential applications in nanotechnology research [21][22][23][24][25][26]. Moreover, this nanomaterial exhibits great potential as a green catalyst in itself, or as catalyst support for a variety of chemical reactions [27].…”