Gold biomineralization by a metallophore from a gold-associated microbe

Abstract

Microorganisms produce and secrete secondary metabolites to assist in their survival. We report that the gold resident bacterium Delftia acidovorans produces a secondary metabolite that protects from soluble gold through the generation of solid gold forms. This finding is the first demonstration that a secreted metabolite can protect against toxic gold and cause gold biomineralization.

Laser-targeted photofabrication of gold nanoparticles inside cells

“…These processes occurring in cells should raise the overall background level of particles, but occur over longer time scales than the photoreduction results presented here, allowing us to confine the reduction to a laser focus region (Figs 2a and 3a). In bacteria, specific molecules involved with gold reduction have recently been identified 29 , while in non-biological environments, laser photoreduction to create metallic microstructures has been demonstrated and the corresponding reduction pathways are more amenable to experimental analysis 30,31 . While the photoreduction pathway in the cellular environment is not obvious, the results here show clearly that even with light, the presence of cellular components is required.…”

Advanced AuNMs as nanomedicine’s central goals capable of active targeting in both imaging and therapy in biomolecules

“…Noteworthy, some novel synthesis strategies, such as biosynthesis [52,53], 2D immiscible oil/water interface [54], levitated leidenfrost drop [55], sunlight-induced synthesis [56] and so on, have been reported, and such green and economic synthesis methods for preparation of uniform and controlled AuNMs provide the opportunity for development of low-cost and sustainable analytical techniques. However, the above technologies need to be further improved and standardized.…”

A Brief Review on Nanoparticles: Types of Platforms, Biological Synthesis and Applications

“…The table also illustrates the location of the nanoparticles in relation to the cells and the suggested method of synthesis (Figure 2). [48] Rhodococcus species Au Intracellular Reduction [49] Escherichia coli Pd, Pt Extracellular Reduction [50] Rhodopseudomonas capsulata Au Extracellular Reduction [42] Pseudomonas aeruginosa Au Extracellular Reduction [51] Delftiaacidovorans Au Extracellular Reduction [41] Bacillus licheniformis Ag Intracellular Reduction [43] Shewanella sp. AsS Extracellular Reduction [52] Shewanella sp.…”

“…The extracellular formation of gold nanoparticles of 10-20 nm size was synthesized by the bacterium Rhodo Pseudomonas capsulate. These nanoparticles were synthesised by an NADH-Dependant Reductase [41] . It has been illustrated that bacteria found at Alpine sites have the capability to produce zero valent palladium (Pd0) nanoparticles.…”