The selection of liver resection surgery for adult patients with colorectal cancer liver metastases is a complex process influenced by various patient, tumor, and surgical factors. A systematic review was conducted with the PICO model research question, "are hepatectomy surgeries more effective than non-surgical treatment or alternative surgical treatments in improving survival and quality of life in adult patients?". A comprehensive scientific literature search was conducted using recognized medical and scientific databases. A narrative-question-answer synthesis was used to provide a comprehensive overview of the factors influencing the choice of hepatic recession surgery in adult patients with liver metastatic liver cancer. Concluding, the choice of liver surgery in adults with liver cancer metastasis depends on a wide range of factors such as the patient's age, characteristics of the tumor, peri and postoperative complications, and the number of metastases. Considering this is essential to the decision-making process and should be individualized for each patient.