GnRH analogs: Options for endometriosis-associated pain treatment

Impact of GnRH agonist treatment on recurrence of ovarian endometriomas after conservative laparoscopic surgery

“…16). In contrast,Busacca et al (20) reported almost equal rates (4 of 44 vs. 4 of 45), similar to the present retrospective study (6 of 37 vs 5 of 28).…”

“…The GnRH agonist medications are one of the medical options used for treatment (16). These medications are frequently used in women with extensive and invasive endometriosis.…”

Review: Gonadal functioning and preservation of reproductive fitness with juvenile systemic lupus erythematosus

“…After initial use in the treatment of males with prostate cancer, GnRH antagonists are already used for the treatment of female infertility and endometriosis; a promising animal study suggests that GnRH antagonist can protect ovarian tissues from the damaging effects of cyclophosphamide. [79][80][81] Besides GnRH-a, and potentially GnRH antagonists, other options to preserve the fertility of young females with jSLE are limited. This is different for mature women, from whom oocytes can be harvested, immediately fertilized and the resulting embryos be preserved until future in vitro fertilization.…”

Possible involvement of nerve growth factor in dysmenorrhea and dyspareunia associated with endometriosis

“…related pain have been extensively investigated [3][4][5][6][7][8]. Various humoral factors including prostaglandins and inflammatory cytokines locally produced in the lesions have been offered as causative factors for the pain.…”