GnRH-Analoga in der Reproduktionsmedizin

Dorn, Christoph; Griesinger, G.

doi:10.1007/s10304-009-0321-x

Cited by 1 publication

(1 citation statement)

References 26 publications

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“…In sheep, the hormonal efficacy was first tested by intravenous application of the compounds used in Improvac ® , then of the complete antigen, in order to measure the LH release. The GnRH fragment itself only had a potency of 0.2% on LH-release when compared to injections of the natural GnRH [128], as the first amino acid, which is involved in receptor binding, is missing [129]. The diphtheria toxoid has also been used for other vaccines and has neither toxic nor hormonal activity [127].…”

Section: Societal Concerns and Immunocastrationmentioning

confidence: 99%

Sustainability of Pork Production with Immunocastration in Europe

et al. 2019

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Immunocastration, a technique to replace surgical castration of piglets, consists of two consecutive vaccinations to induce antibodies which transiently suppress testicular functions and avoid boar taint. It is a method to ensure both a high product quality and a high level of animal welfare. The impact of immunocastration on the three pillars of sustainability has been studied extensively. While all aspects of sustainability have been studied separately, however, a contemporary global overview of different aspects is missing. In immunocastrates, performance results are better than in barrows, but worse than in boars. The environmental impact of pork production with immunocastrates is lower than with barrows, but higher than with boars. The level of aggression is considerably lower in immunocastrates compared to boars. Societal concerns are mainly related to food safety, and are not supported by scientific evidence. After second vaccination, immunocastrates switch from a boar- to a barrow-like status. Therefore, the timing of second vaccination is a fine-tuning tool to balance advantages of boars with environmental and economic benefits against increased risk of welfare problems and boar taint. Nevertheless, both synergic and conflicting relationships between the pillars of sustainability must be communicated along the value chain to produce tailored pork products.

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Section: Societal Concerns and Immunocastrationmentioning

confidence: 99%