Gnatophyma: A rare rosacea phyma variant

Two Cases of Gnatophyma, an Unusual Form of Rosacea

“…Gnatophyma is a sporadically identified phyma variant in the literature with both clinical and histopathological characteristics which is difficult to diagnose because of the rarity of its occurrence. Gnatophyma may appear alone or coexist with rosacea lesions [4,5,6]. It has been rarely reported indeed.…”

Gnatophyma: a rare form of rosacea

“…3 The clinical severity of the phyma variant is based on the deformity degree. 4 Gnatophyma has been rarely reported, there are only three cases in the scientific literature, and it may manifest alone or coexist with rosacea lesions. 4,5,6 In those reported cases, one patient is male and two are female, and all of them have injuries exclusively on the chin.…”

“…7 Demodex was found in two of three cases mentioned in scientific literature and its presence in rosacea may be due to localized immune deficiency caused by lymphoedema and / or Demodex could serve as a source for antigenic persistent inflammation. 4,5,6 These hypotheses explain the predisposition to the development of skin cancer on phyma. 7 There are few reports in literature that show association between rosacea and dental diseases.…”

“…1,2,3 To treat the severe type of phyma one can make use of carbon dioxide laser and surgery. 3,4,5,6 Due to the rare occurrence of gnatophyma, the ideal treatment still represents a challenge. The treatment prescribed was tetracycline 1g / day, ivermectin 12 mg single dose, and metronidazole cream 1%.…”

Gnatophyma and Otophyma

“…1 These variant phymas are sporadically identified in the literature, but images of these variants are not often seen. 2 We report two rare phymas: a case of gnatophyma and a case of otophyma.…”