Glymphatic dysfunction and choroid plexus volume increase in older adults with poor sleep quality
Junko Kikuta
Abstract:Objective
This study aimed to explore alterations in diffusion tensor image analysis along the perivascular space (DTI-ALPS) method and choroid plexus volume (CPV), which could be biomarkers of the glymphatic system in older adults with poor sleep quality (PSQ).
Methods
Fifty-two Japanese older adults with Pittsburgh Sleep Quality Index (PSQI) scores > 5 (22 men and 30 women; mean age ± SD = 73.10 ± 5.67 years) and 52 healthy controls (HCs; PSQI score ≤ 5) were included. Diffusion-weighted imaging (DWI) a… Show more
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