Glycopyrronium Bromide In The Treatment Of Chronic Gastric Ulcer

Baume, Peter; Hunt, John H.; Piper, D. W.

doi:10.1016/s0016-5085(19)33277-9

Cited by 29 publications

(2 citation statements)

References 27 publications

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“…The most relevant to the present study is the detailed and extensive study conducted by the Veterans Administration (Littman, 1971;Hanscom and Buchman, 1971; Sun and Stempien, 1971 Gott, Shapiro, and Kelty (1954) observed 86 patients whose ulcers had healed medically; two to five years later 14 had recurred. Baume, Hunt, and Piper (1972) observed a recurrence rate of 77 % after initial complete healing within two years in a placebotreated group of gastric ulcer patients. Dworken, Roth, Duber, and Berger (1957) observed a recurrence rate of 80% in 135 patients followed for 3 9 years after healing of the ulcer.…”

Section: Discussionmentioning

confidence: 88%

“…The failure of cigarette smoking to influence adversely the course of peptic ulcer was not unexpected in view of recent data (Whitecross, Clarke, and Piper, 1973) but the lack of effect of analgesic ingestion was unexpected, considering the data available to the contrary, especially in Australia (Baume et al, 1972;Duggan, 1972).…”

Section: Cigarette Smoking and Analgesic Ingestionmentioning

confidence: 95%

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Factors relevant to the prognosis of chronic gastric ulcer.

Piper¹,

Greig²,

Coupland³

et al. 1975

Gut

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SUMMARY The factors that determine the recurrence rate of chronic gastric ulcer were studied in 105 patients. It was found that complete healing of the ulcer significantly reduced the recurrence rate and subsequent need for hospital admission because of ulcer symptoms when this group was compared with those who left hospital with their ulcers unhealed. Those admitted with large ulcers also had a higher recurrence rate. The age and sex of the patient, ingestion of analgesics and cigarette smoking did not influence recurrence. The initial healing rate of the ulcer also had no effect on the subsequent course of the patient.

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Section: Discussionmentioning

confidence: 88%

Section: Cigarette Smoking and Analgesic Ingestionmentioning

confidence: 95%