Glycopolymer Nanobiotechnology

Synthesis and characterization of sugar-based methacrylates and their random copolymers by ATRP

“…A little differences between GPC and 1 H-NMR data were usually observed for the differences in hydrodynamic volume of copolymer's components, in which sugar-based methacrylates had considerably dissimilar structures as compared to the MMA. The thermal properties of the obtained random copolymers were evaluated using the glass transition temperatures (T g ) determined by DSC (Table 1) all copolymers exhibited relatively similar Tg g values between 101.2 and 102.9°C (entry [1][2][3][4]. This differences could be related to either the molecular weight differences or nature of random copolymer with nonuniform composition, which was previously reported by other groups [52][53][54].…”

Complete lignocellulose conversion with integrated catalyst recycling yielding valuable aromatics and fuels

“…Compound 7 may serve as a building block in various glycopolymers used for drug or gene delivery systems 45 . Due to the similar structure to vanillin alcohol, 1G can also be used for synthesis of bisphenols, epoxy resins, polyesters or polyurethanes 43 .…”

Construction of Functional Biomaterials by Biomolecular Self-Assembly

“…69 So far, artificial glycoclusters based on synthetic polymers showing such a multivalent glycocluster effect have been developed, not only as a model of molecular recognition involving glycolipids and glycoproteins but also as a cell culture substrate, material for trapping viruses and toxins, sensing material, drug delivery material, and regulating material of amyloid fibrils. 9 In densely arranged glycoclusters based on synthetic homopolymers such as polystyrene and polyacrylamide as the main chain, the lectin-recognizing ability may decrease due to steric hindrance in some cases. 10 Although copolymerization can space the oligosaccharides on average intervals, it is difficult to synthesize macromolecules in which the intervals of oligosaccharides are regularly controlled ( Figure 1A).…”