Glycopeptide-resistant enterococci in Northern Ireland: first reported outbreak

Rizkalla, Essam; Moore, J.; Marshall, Steven A.; Murphy, Philip G.

doi:10.1093/jac/40.4.607

Cited by 4 publications

(2 citation statements)

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“…However, after full-text reading 3 more articles had to be excluded, two articles because they did not clearly distinguish between hematology/oncology patients and patients from other medical departments ( Kurup et al, 2008 ) ( Hwang et al, 1998 ) and one article because it described an endemic situation rather than an epidemic setting ( Park et al, 2011 ). Thus, eventually 35 articles ( Böröcz et al, 2005 ; Burnie et al, 2002 ; Chadwick et al, 1996 ; Chlebicki et al, 2006 ; Deplano et al, 2007 ; Edmond et al, 1995 ; Gambarotto et al, 2000 ; Hanna et al, 2001 ; Iosifidis et al, 2012 ; Kawalec et al, 2000 ; Kawalec et al, 2001 ; Kawalec et al, 2007 ; Knoll et al, 2005 ; Lavery et al, 1997 ; Lesens et al, 2006 ; Loeb et al, 1999 ; Marcade et al, 2014 ; McCarthy et al, 2000 ; Montecalvo et al, 1994 ; Nolan et al, 2009 ; Nourse et al, 1998 ; Oh et al, 2004 ; Ozorowski et al, 2009 ; Pendle et al, 2008 ; Rizkalla et al, 1997 ; Rubin et al, 1992 ; Sample et al, 2002 ; Schmidt-Hieber et al, 2007 ; Schuster et al, 1998 ; Singh-Naz et al, 1999 ; Timmers et al, 2002 ; Valdezate et al, 2012 ; Wardal et al, 2014 ; Worth et al, 2007 ; Yoo et al, 2005 ) were considered appropriate for inclusion for further analysis ( Fig. 1 ).…”

Section: Resultsmentioning

confidence: 99%

Outbreaks caused by vancomycin-resistant Enterococcus faecium in hematology and oncology departments: A systematic review

Ulrich

Vonberg

Gastmeier

2017

Heliyon

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BackgroundVancomycin-resistance in Enterococcus faecium (VRE) poses a major threat in health care settings. It is well known that patients in hematology and oncology departments are especially at risk of nosocomial VRE acquisition. This systematic review of the literature provides data on the main sources, transmission modes and potential risk factors for VRE acquisition as well as appropriate infection control measures in order to terminate such nosocomial outbreaks.MethodsData on nosocomial VRE outbreaks on hematology and oncology wards was retrieved from the Outbreak Database and PubMed.ResultsA total of 35 VRE outbreaks describing 757 affected patients and 77 deaths were included in this review. The most frequent site of pathogen detection were stool samples or rectal swabs (57% of all isolation sites), followed by blood cultures (30%). The most common outbreak source was an index patient. The main modes of transmission were 1) hands of health care workers, 2) contact to a contaminated environment and 3) patient-to-patient contact. The most common risk factor for VRE positivity was prior antibiotic treatment. The most common infection control measures performed were screening and isolating or cohorting of patients.ConclusionA rational use of antibiotics in hematology and oncology units is recommended in order to reduce selection pressure on resistant pathogens such as VRE. In addition the importance of hand hygiene should be stressed to all staff whenever possible.

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Section: Resultsmentioning

confidence: 99%

Outbreaks caused by vancomycin-resistant Enterococcus faecium in hematology and oncology departments: A systematic review

Ulrich

Vonberg

Gastmeier

2017

Heliyon

View full text Add to dashboard Cite

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“…Our search yielded 36 outbreaks appropriate for this study [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49]. The mean duration of 31 outbreaks with information about its duration was 11 months (range 1 to 36 months).…”

Section: Resultsmentioning

confidence: 99%