Glycolic Acid Peels Versus Salicylic-Mandelic Acid Peels in Active Acne Vulgaris and Post-Acne Scarring and Hyperpigmentation: A Comparative Study

Garg, Vijay Kumar; Sinha, Surabhi; Sarkar, Rashmi

doi:10.1111/j.1524-4725.2008.34383.x

Cited by 58 publications

(58 citation statements)

References 17 publications

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“…It is an ideal peeling agent for sensitive skin and is well tolerated and more effective as compared to the traditional GA peels, in acne, postacne scarring, and pigment dyschromias. 3,9 Salicylic acid peels are well tolerated in all skin types (Fitzpatrick I to VI) and in all racial/ ethnic groups and are excellent peeling agents for numerous conditions including acne, melasma, and PIH in dark-skinned individuals. 2, 8 Grimes 10 successfully demonstrated the efficacy and safety of 20% to 30% SA peel in patients of melasma with skin types V and VI, however, another randomized control split face trial found them to be ineffective in the treatment of melasma.…”

Section: Discussionmentioning

confidence: 99%

Comparative Evaluation of Efficacy and Tolerability of Glycolic Acid, Salicylic Mandelic Acid, and Phytic Acid Combination Peels in Melasma

Sarkar

Garg²,

Bansal³

et al. 2016

Dermatologic Surgery

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Section: Discussionmentioning

confidence: 99%

Comparative Evaluation of Efficacy and Tolerability of Glycolic Acid, Salicylic Mandelic Acid, and Phytic Acid Combination Peels in Melasma

Sarkar

Garg²,

Bansal³

et al. 2016

Dermatologic Surgery

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“…However, in a second study there were no significant differences in effectiveness between GA and SA. 14,15 …”

Section: Resultsmentioning

confidence: 99%

“…9 However, Garg et al found that GA had a lower efficacy than SA in treatment of active acne vulgaris (P<0.001) and hyperpigmentation (P<0.001) since GA don't have anti-inflammatory effects hence making it lower rank to SA in the treatment of acne lesions. 14 Another chemical peel used in treatment of acne vulgaris is SA which is a Beta-hydroxyl acid with both keratolytic properties and anti-inflammatory also could infiltrate simply to pilosebaceous layers and is not toxic, self-neutralizing with minimal dermal infiltration. 20 Previous study showed that SA can be used for all stages of active acne due to its anti-inflammatory and comedolytic properties.…”

Section: Discussionmentioning

confidence: 99%

Efficacy and safety of superficial chemical peeling in treatment of active acne vulgaris

Al-Talib

Al-Khateeb

Hameed

et al. 2017

An. Bras. Dermatol.

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Acne vulgaris is an extremely common condition affecting the pilosebaceous unit of the skin and characterized by presence of comedones, papules, pustules, nodules, cysts, which might result in permanent scars. Acne vulgaris commonly involve adolescents and young age groups. Active acne vulgaris is usually associated with several complications like hyper or hypopigmentation, scar formation and skin disfigurement. Previous studies have targeted the efficiency and safety of local and systemic agents in the treatment of active acne vulgaris. Superficial chemical peeling is a skin-wounding procedure which might cause some potentially undesirable adverse events. This study was conducted to review the efficacy and safety of superficial chemical peeling in the treatment of active acne vulgaris. It is a structured review of an earlier seven articles meeting the inclusion and exclusion criteria. The clinical assessments were based on pretreatment and post-treatment comparisons and the role of superficial chemical peeling in reduction of papules, pustules and comedones in active acne vulgaris. This study showed that almost all patients tolerated well the chemical peeling procedures despite a mild discomfort, burning, irritation and erythema have been reported; also the incidence of major adverse events was very low and easily manageable. In conclusion, chemical peeling with glycolic acid is a well-tolerated and safe treatment modality in active acne vulgaris while salicylic acid peels is a more convenient for treatment of darker skin patients and it showed significant and earlier improvement than glycolic acid

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“…Other α-hydroxy acids such as mandelic acid are used in skin peels fort the treatment of acne vulgaris. 8 The afore mentioned applications justify the need of a fast, selective and easy to prepare instrumental method for the chiral determination of α-hydroxy acids.…”

Section: Introductionmentioning

confidence: 99%

Chiral Separation of α-hydroxy Acids by Capillary Electrochromatography Using the Cathodic Detergent CTAB as Mobile Phase Additive to Speed up Analysis Time

Mohr¹,

Sepic²,

Schmid³

2012

Croat. Chem. Acta

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Abstract. In order to speed up the analysis time, working with negatively charged compounds in capillary electromigration techniques often requires to change direction of the EOF. Negatively charged compounds intend to migrate towards the anode and are normally retained by the counter migrating EOF. Therefore the positively charged detergent cetyltrimethylammoniumbromide (CTAB) was used as mobile phase additive for the chiral separation of α-hydroxy acids in capillary electrochromatography (CEC). A 25 % particle loaded Ristocetin A continuous bed (CB) was used as stationary phase to separate a set of mandelic acid derivatives. Using mandelic acid and 4-bromo-mandelic acid as model substances the effect of different CTAB concentrations in the mobile phase on the migration time and the resolution was tested. It could be shown that with an increasing concentration of the CTAB the migration time decreased. The addition of CTAB to the mobile phase is a serious alternative to copolymerizing an anionic charge providing substances such as diallyl dimethylammonium chloride (DADMAC) in CB technology. (doi: 10.5562/cca1902)

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Glycolic Acid Peels Versus Salicylic-Mandelic Acid Peels in Active Acne Vulgaris and Post-Acne Scarring and Hyperpigmentation: A Comparative Study

Cited by 58 publications

References 17 publications

Comparative Evaluation of Efficacy and Tolerability of Glycolic Acid, Salicylic Mandelic Acid, and Phytic Acid Combination Peels in Melasma

Comparative Evaluation of Efficacy and Tolerability of Glycolic Acid, Salicylic Mandelic Acid, and Phytic Acid Combination Peels in Melasma

Efficacy and safety of superficial chemical peeling in treatment of active acne vulgaris

Chiral Separation of α-hydroxy Acids by Capillary Electrochromatography Using the Cathodic Detergent CTAB as Mobile Phase Additive to Speed up Analysis Time

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