Glycerol group substituted bis(2-pyridylimino)isoindoline (BPI) complexes: synthesis, characterization and investigation of their biological properties

Kaşıkçı, Asena; Katırcı, Ramazan; Özdemir, Sadin; Yalçın, M. Serkan; Özçeşmeci, Mukaddes

doi:10.1039/d3dt01481a

Dalton Trans.

2023

DOI: 10.1039/d3dt01481a

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Glycerol group substituted bis(2-pyridylimino)isoindoline (BPI) complexes: synthesis, characterization and investigation of their biological properties

Asena Kaşıkçı,

Ramazan Katırcı,

Sadin Özdemir

et al.

Abstract: In this study, glycerol group substituted bis(2-pyridylamino)isoindoline (BPI-OH) ligand and its metal complexes (M = Pt, Cu and Co) were synthesized. Characterization of all new compounds was carried out using...

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2024

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Cited by 3 publications

References 55 publications

(75 reference statements)

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Investigation of the treatment and antibacterial properties of pollutant-containing water using black phosphorus blended polyethersulfone membranes (BP@PES)

Eskikaya,

Kucukosman,

Ozdemir

et al. 2024

Journal of Water Process Engineering

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Investigation of the treatment and antibacterial properties of pollutant-containing water using black phosphorus blended polyethersulfone membranes (BP@PES)

Eskikaya,

Kucukosman,

Ozdemir

et al. 2024

Journal of Water Process Engineering

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The effect of metal type and gamma irradiation doses on the VOC detection performance of new 1,3-bis(2-pyridylamino)isoindoline complexes

Gümrükçü,

Urfa,

Altındal

et al. 2024

Journal of Molecular Structure

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Biological Performance of Hexadeca-Substituted Metal Phthalocyanine/Reduced Graphene Oxide Nanobioagents

Farajzadeh Öztürk,

Özdemir,

Yalçın

et al. 2024

ACS Appl. Bio Mater.

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This study presents a tetra-substituted phthalonitrile derivative, namely, diethyl 2-(3,4dicyano-2,5-bis(hexyloxy)-6-(4-(trifluoromethoxy)phenoxy)phenyl)malonate (a), cyclotetramerizing in the presence of some metal salts. The resultant hexadeca-substituted metal phthalocyanines [M= Co, Zn, InCl)] (b−d) were used for the modification of reduced graphene oxide for the first time. The effect of the phthalonitrile/metal phthalocyanines on biological features of reduced graphene oxide (rGO) was extensively examined by the investigation of antioxidant, antimicrobial, DNA cleavage, cell viability, and antibiofilm activities of nanobioagents (1−4). The results were compared with those of unmodified rGO (nanobioagent 5), as well. Modification of reduced graphene oxide with the synthesized compounds improved its antioxidant activity. The antioxidant activities of all the tested nanobioagents also enhanced as the concentration increased. The antibacterial activities of all the nanobioagents improved by applying the photodynamic therapeutic (PDT) method. All the phthalonitrile/phthalocyanine-based nanobioagents (especially phthalocyanine-based nanocomposites) exhibited DNA cleavage activities, and complete DNA fragmentation was observed for nanobioagents (1−4) at 200 mg/L. They can be used as potent antimicrobial and antimicrobial photodynamic therapy agents as well as Escherichia coli microbial cell inhibitors. As a result, the prepared nanocomposites can be considered promising candidates for biomedicine.

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Glycerol group substituted bis(2-pyridylimino)isoindoline (BPI) complexes: synthesis, characterization and investigation of their biological properties

Abstract: In this study, glycerol group substituted bis(2-pyridylamino)isoindoline (BPI-OH) ligand and its metal complexes (M = Pt, Cu and Co) were synthesized. Characterization of all new compounds was carried out using...

Cited by 3 publications

References 55 publications

Investigation of the treatment and antibacterial properties of pollutant-containing water using black phosphorus blended polyethersulfone membranes (BP@PES)

Investigation of the treatment and antibacterial properties of pollutant-containing water using black phosphorus blended polyethersulfone membranes (BP@PES)

The effect of metal type and gamma irradiation doses on the VOC detection performance of new 1,3-bis(2-pyridylamino)isoindoline complexes

Biological Performance of Hexadeca-Substituted Metal Phthalocyanine/Reduced Graphene Oxide Nanobioagents

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