Glycerol dehydration of native and diabetic animal tissues studied by THz-TDS and NMR methods

Smolyanskaya, O. A.; Schelkanova, Irina; Kulya, Maksim S.; Odlyanitskiy, E. L.; Goryachev, I. S.; Tcypkin, Anton; Grachev, Ya. V.; Toropova, Yana; Tuchin, Valery V.

doi:10.1364/boe.9.001198

Cited by 63 publications

(26 citation statements)

References 51 publications

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“…Terahertz (THz) frequency range is finding more and more applications in different fields of fundamental research [1] and a variety of everyday applications such as nondestructive spectroscopy [2] and imaging [3], communications [4,5] and ultrafast control [6] as well as biomedicine [7]. Recent advances in research have brought high intensity broadband sources of THz radiation into play [8].…”

Section: Introductionmentioning

confidence: 99%

High Kerr nonlinearity of water in THz spectral range

Tcypkin¹,

Melnik²,

Zhukova³

et al. 2019

Opt. Express

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The values of the nonlinear refractive index coefficient for various materials in the terahertz frequency range exceed the ones in both visible and NIR ranges by several orders of magnitude. We report the direct measurement of the nonlinear refractive index coefficient of liquid water by using the Z-scan method with broadband pulsed THz beam. Our experimental result shows that nonlinear refractive index coefficient in water is positive and can be as large as 3.5×10 −10 cm 2 /W in the THz frequency range, which exceeds the ones for the visible and NIR ranges by 6 orders of magnitude.

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Section: Introductionmentioning

confidence: 99%

High Kerr nonlinearity of water in THz spectral range

Tcypkin¹,

Melnik²,

Zhukova³

et al. 2019

Opt. Express

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“…Several research groups have investigated excised and fixed tissues considering numerous approaches; among them are dehydration [146,147], alcohol perfused [36], formalin fixed [148][149][150], gelatin embedding [151,152], lyophilized [153], freezing [154,155] and fixation in paraffin emulsion and embedding [156].…”

Section: Thz Pulsed Imaging: Uses Advantages and Challenges For Biommentioning

confidence: 99%

THz Pulsed Imaging in Biomedical Applications

et al. 2020

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Recent advances in technology have allowed the production and the coherent detection of sub-ps pulses of terahertz (THz) radiation. Therefore, the potentialities of this technique have been readily recognized for THz spectroscopy and imaging in biomedicine. In particular, THz pulsed imaging (TPI) has rapidly increased its applications in the last decade. In this paper, we present a short review of TPI, discussing its basic principles and performances, and its state-of-the-art applications on biomedical systems.

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“…Thus taking less computation time for numerical reconstruction. This technique is preferable for the analysis of light diffraction by histological slides [3]. Angular spectrum representation consists of the following stages: (i) the representation of the field through the angular spectrum of 2D waves (Eq.1); (ii) multiplication by the transfer function that contains a complex refractive index of the object (Eq.2); (iii) the back transition from plane waves to the wave field in the calculated z-plane (Eq.3).…”

Section: Model Of Wavefront Propagationmentioning

confidence: 99%