Glycemic control may be influenced by climate changes in type 2 diabetes mellitus (T2DM)

Abstract

Authors have continued clinical research on type 2 diabetes mellitus (T2DM). The trigger of this research was to make notice of elevated HbA1c of younger male diabetics for hot climate in the summer 2018. Enrolled subjects were 89 male patients with T2DM. Methods include the classification of 6 groups by the age, which are 21-40, 41-50, 51-60, 61-70, 71-80 and 81-90. HbA1c values in median were calculated for five seasons of 15 months. Basal HbA1c in 6 groups was 7.0%, 7.1%, 7.2%, 7.2%, 6.9% and 7.0%, respectively. Seasonal changes in HbA1c values are as follows: i) groups 21-50 showed highest in the summer, ii) groups 51-70 showed gradually decrease from winter to summer, iii) groups 71-90 showed gradually decrease from winter to autumn, and increase for winter. For seasonal HbA1c changes, influence of hot climate during from spring to summer may be involved for 21-50 years. More activity in spring to summer may be related for 51-70 years. Less exercise and more eating may be observed for 71-90 years. There are not enough analyze for related factors, then further study concerning various biomarkers would be expected.

Evaluation of the diagnosed incidental diabetes mellitus in patients with hyperglycaemia in the emergency department

“…In a study by Katsarou et al, 16 it was found that the blood glucose levels were the lowest in winter and the highest in summer. In the study where Bando et al, investigated the relation between seasonal variability and HbA1c in Japan, it was found that HbA1c increased in the summer months and decreased in the autumn months 17 . In another study, the seasonal changes and the length of the seasons were thought to be effective on the frequency of DM.…”

“…In the study where Bando et al, investigated the relation between seasonal variability and HbA1c in Japan, it was found that HbA1c increased in the summer months and decreased in the autumn months. 17 In another study, the seasonal changes and the length of the seasons were thought to be effective on the frequency of DM. Unlike the literature, the long period of winter in the Kars province caused approximately 40% of our patients to be detected in this season.…”

Seasonal Variation of Glucose Variability in Rather Elderly Patients with Type 2 Diabetes (T2D) Treated by Vildagliptin and Metformin (EquMet)

“…Authors and colleagues have continued clinical practice and research on T2D for seasonal influence and pharmacological treatment [7,8]. Recently, we have focused on the protocol that includes rather elderly T2D patients and a common combination of vildagliptin and metformin among various combinations of treatments [9].…”

Various roles of renal rehabilitation including prevention and improvement of renal function, cardiovascular disease, flail and life prognosis

“…7 Authors and colleagues have conducted clinical studies on patients with diabetes. 8 Furthermore, we have presented reports on chronic renal disease and hemodialysis. 9,10 Renal rehabilitation is characterized by its mutually connected rehabilitation, including pathophysiology of cardiovascular, respiratory, neurology, immunology, metabolism and so on.…”