Glycated Hemoglobin and Risk of Sternal Wound Infection After Isolated Coronary Surgery

Gatti, Giuseppe; Perrotti, Andréa; Reichart, Daniel; Maschietto, Luca; Chocron, Sidney; Dalén, Magnus; Svenarud, Peter; Faggian, Giuseppe; Santarpino, Giuseppe; Fischlein, Theodor; Pappalardo, Aniello; Maselli, Daniele; Dominici, Carmelo; Nardella, Saverio; Rubino, Antonio; Feo, Marisa De; Santini, Francesco; Nicolini, Francesco; Gherli, Riccardo; Mariscalco, Giovanni; Tauriainen, Tuomas; Kinnunen, Esko; Ruggieri, Vito Giovanni; Saccocci, Matteo; Biancari, Fausto

doi:10.1253/circj.cj-16-0778

Cited by 40 publications

(33 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This study confirmed the findings of a few prior studies demonstrating the ability of preoperative levels of HbA1c to predict SWI after coronary surgery [9][10][11]. Since this was not an interventional study, the present findings are only hypothesis-generating.…”

Section: Discussionsupporting

confidence: 92%

“…Optimization of glycemic control seems to reduce the risk of infection [8]. Increased preoperative levels of HbA1c seems to be associated with a higher risk of sternal wound infection (SWI) in patients undergoing coronary artery bypass grafting (CABG) [9][10][11]. However, it is not clear whether HbA1c as an indicator of poor glycemic control may predict other early adverse events after cardiac surgery [12].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Utility of glycated hemoglobin screening in patients undergoing elective coronary artery surgery: Prospective, cohort study from the E-CABG registry

Nicolini

Santarpino

Gatti

et al. 2018

International Journal of Surgery

Self Cite

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 92%

Section: Introductionmentioning

confidence: 99%

Utility of glycated hemoglobin screening in patients undergoing elective coronary artery surgery: Prospective, cohort study from the E-CABG registry

Nicolini

Santarpino

Gatti

et al. 2018

International Journal of Surgery

Self Cite

View full text Add to dashboard Cite

show abstract

“…Smoking cessation is mandatory and confirmed with nicotine tests on follow-up clinic visits and prior to surgery. Glycemic control defined as a hemoglobin A1c less than 7.2% is used on the basis of internal validation for risk calculations as well as international consensus [47][48][49][50][51] . All these interventions are achieved through a healthcare network in conjunction with a multidisciplinary team involving the primary care provider, dietician, bariatricians, bariatric surgeons, and other healthcare providers.…”

Section: Perioperative Managementmentioning

confidence: 99%

Establishing a center of excellence in abdominal wall reconstruction

Shao¹,

Elhage²,

Deerenberg³

et al. 2020

PAR

View full text Add to dashboard Cite

Building a tertiary referral center of excellence for complex abdominal wall reconstruction is a multi-step process that requires many elements to garner and promote success. Ultimately the creation of such a center is important for continual improvement of abdominal wall reconstruction outcomes by decreasing complications, recurrences, length of hospital stay, hospital readmissions, and overall costs. Establishing a center of excellence incorporates several key components including the surgeon's desires and expertise, institutional participation, multidisciplinary collaboration, outcomes research and innovation, and financial stability. This article outlines the principal elements of building a sustainable, functional, and successful center of excellence for complex abdominal wall reconstruction.

show abstract

“…Obese patients have a higher prevalence of diabetes that is a predisposing factor for delayed wound healing and to bacterial infections [23][24][25][26]. In addition, due to the extra-adipose tissue in the subcuticular space, obese patiens are prone to develop seromas that often become infected because of the suboptimal vascularization of the adipose tissue [27][28][29][30].…”

Section: Wound Complications In Obese Patientsmentioning

confidence: 99%

Robotic Versus Open Renal Transplantation in Obese Patients: Protocol for a Cost-Benefit Markov Model Analysis (Preprint)

Molinari¹,

Puttarajappa²,

Wijkstrom³

et al. 2017

Preprint

View full text Add to dashboard Cite

A Markov model will be developed to simulate a randomized controlled study to assess the costeffectiveness of robotic-assisted renal transplantation in comparison to open surgery in obese patients. Project SummaryThe number of patients affected by renal insufficiency and obesity is growing, especially in North America where obesity has reached epidemic proportions. Obesity is associated with several comorbidities that increase the risks of wound complications. Wound infections are one of the most common nosocomial complications in patients who undergo contaminated surgical procedures or who are immunosuppressed or diabetic. Often, obese patients who undergo renal transplantation have diabetes in addition to being immunosuppressed and develop some degree of wound complications (infections, seromas, dehiscence, hernias) in up to 50% of cases. Wound complications represent a significant clinical and economic burden to the health-care system. In particular, wound infections are responsible for longer hospitalizations and decreased functional capacity of renal transplant recipients who require extramural nursing for the management of their wound-vacuum devices and local debridement and packing of their incisions.

show abstract

Glycated Hemoglobin and Risk of Sternal Wound Infection After Isolated Coronary Surgery

Abstract: Screening for HbA1c before CABG may identify untreated diabetic patients, as well as diabetic patients with suboptimal glycemic control, at high risk of SWI.

Cited by 40 publications

References 20 publications

Utility of glycated hemoglobin screening in patients undergoing elective coronary artery surgery: Prospective, cohort study from the E-CABG registry

Utility of glycated hemoglobin screening in patients undergoing elective coronary artery surgery: Prospective, cohort study from the E-CABG registry

Establishing a center of excellence in abdominal wall reconstruction

Robotic Versus Open Renal Transplantation in Obese Patients: Protocol for a Cost-Benefit Markov Model Analysis (Preprint)

Contact Info

Product

Resources

About