Glycated Haemoglobin: A Predictor of Vascular Risk?

Rizos, Evagelos; Mikhailidis, D. P.

doi:10.1159/000497534

Cited by 2 publications

(2 citation statements)

References 32 publications

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“…Fibrates also increase HDL-C and this effect was independently associated with reduced risk of events in both primary and secondary prevention studies [64][65][66][67]. Therefore, combining fibrates with a statin may be an effective therapeutic option [12][13].…”

Section: B Effect Of Using Statins Combined With Other Drugs On Hdl-mentioning

confidence: 99%

High Density Lipoprotein Cholesterol and Statin Trials

Kakafika

Athyros²,

Τζιόμαλος³

et al. 2008

CMC

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Epidemiological studies show that high density lipoprotein cholesterol (HDL-C) levels are inversely related to the risk of vascular events. Statins are the most widely prescribed drugs for the treatment of dyslipidaemias and their use for the prevention of vascular events is evidence based. Statins raise HDL-C but this effect seems to vary considerably between studies. We searched the literature to assess the relationship between statin-induced increases in HDL-C levels and surrogate and/or clinical endpoints. Based on the existing evidence, it is difficult to determine how much reduction, if any, in vascular risk is attributable to a statin-induced increment in HDL-C levels. Whether a statin that beyond its LDL-C lowering effect also raises HDL-C has additional benefits in the prevention of vascular events remains to be established.

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Section: B Effect Of Using Statins Combined With Other Drugs On Hdl-mentioning

confidence: 99%

High Density Lipoprotein Cholesterol and Statin Trials

Kakafika

Athyros²,

Τζιόμαλος³

et al. 2008

CMC

View full text Add to dashboard Cite

show abstract

“…Moreover, walking 5 km a day that takes approximately 90 minutes can improve up to 1.1% he-moglobin A1C (Karstoft et al 2012). Reduction in glycosylated hemoglobin A1C has lots of benefits in reducing cardiovascular complications (Rizos & Mikhailidis 2001); each 1% increase in glycosylated hemoglobin is associated with 18% increase in cardiovascular disease risk. Therefore, aerobic exercise can be an ideal exercise for people with diabetes (Sigal et al 2007).…”

Section: Introductionmentioning

confidence: 99%

Factors Associated With Fear of Falling and Functional Independence in Older Adult Living in an Iranian Nursing Home: A Cross-Sectional Study

Bastani

Birjandi

Haghani

et al. 2016

JCCNC

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Background: Fear of falling is common amongst older adults, especially those who live in nursing homes. This study aimed to determinate factors associated with fear of falling and functional independence in older adults living in nursing homes. Methods: This was a cross-sectional study using a convenience sampling method to enroll 200 older adults living in nursing homes from 25 senior centers in Tehran (districts 1 and 2) between September 2015 and November 2015. Main outcome measurement instruments were the 16item falls efficacy scale international (FES-I, Persian version) and 11-item Barthel index (BI) functional independence measure. In this study, variables were analyzed using Student t test and ANOVA. The Pearson coefficient correlation was used to examine the relationship between FES and BBS. A 2-tailed P < 0.05 was considered statistically significant. Results: The participants were mostly female (51.5%) and aged over 70 (mean age 76.89 ± 8.50 y). Of 200 seniors within the study, 60.8% experienced one or more falls during the last year. Statistically significant relationships were found between the fear of falling and functional independence (r =-0.524; P ≤ 0.001). There was a significant relationship between fear of falling and age (P = 0.039), history of falling (P = 0.002), and chronic disease (P = 0.009). In addition, there was a significant relationship between functional independence and some older adults' characteristics, such as gender (P = 0.048), education level (P = 0.028), duration of living in nursing home (P = 0.002), history of falling (P = 0.006), and chronic disease (P = 0.01). Conclusion: According to the findings, there was a high level of fear of falling in the older adults. The fear of falling in the older adults living in nursing homes is associated with age, history of falling, and chronic disease. There was a significant association between functional independence and variables of gender, education level, duration of living in nursing home, history of falling, and chronic disease.

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Glycated Haemoglobin: A Predictor of Vascular Risk?

Cited by 2 publications

References 32 publications

High Density Lipoprotein Cholesterol and Statin Trials

High Density Lipoprotein Cholesterol and Statin Trials

Factors Associated With Fear of Falling and Functional Independence in Older Adult Living in an Iranian Nursing Home: A Cross-Sectional Study

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