Glycaemic control in type 2 diabetes patients and its predictors: a retrospective database study at a tertiary care diabetes centre in Ningbo, China

Abstract

ObjectivesThe objectives of the study were to assess glycaemic control in patients with type 2 diabetes (T2DM) at a tertiary care diabetes centre in Ningbo, China and to determine factors that independently predict their glycaemic control.DesignRetrospective cross-sectional study using an existing database, the Diabetes Information Management System.SettingTertiary care diabetes centre in Ningbo, China.ParticipantsThe study included adult patients with T2DM, registered and received treatment at the diabetes centre for at least six consecutive months. The study inclusion criteria were satisfied by 1387 patients, from 1 July 2012 to 30 June 2017.Primary outcome measureGlycaemic control (poor was defined as glycated haemoglobin (HbA1c)>=7% or fasting blood glucose (FBG)>7.0 mmol/L).ResultsIn terms of HbA1c and FBG, the 5-year period prevalence of poor glycaemic control was 50.3% and 57.3%, respectively. In terms of HbA1c and FBG, the odds of poor glycaemic control increased with the duration of T2DM (>1 to 2 years: OR 1.84, 95% CI 1.06 to 3.19; >2 to 4 years: 3.32, 1.88 to 5.85 and >4 years: 5.98, 4.09 to 8.75 and >1 to 2 years: 2.10, 1.22 to 3.62; >2 to 4 years: 2.48, 1.42 to 4.34 and >4 years: 3.34, 2.32 to 4.80) and were higher in patients residing in rural areas (1.68, 1.24 to 2.28 and 1.42, 1.06 to 1.91), with hyperlipidaemia (1.57, 1.12 to 2.19 and 1.68, 1.21 to 2.33), on diet, physical activity and oral hypoglycaemic drug (OHD) as part of their T2DM therapeutic regimen (1.80, 1.01 to 3.23 and 2.40, 1.36 to 4.26) and on diet, physical activity, OHD and insulin (2.47, 1.38 to 4.41 and 2.78, 1.58 to 4.92), respectively.ConclusionsMore than half of patients with T2DM at the diabetes centre in Ningbo, China have poor glycaemic control, and the predictors of glycaemic control were identified. The study findings could be taken into consideration in future interventional studies aimed at improving glycaemic control in these patients.

Risk Factors of Type 2 Diabetes Mellitus Duration and Non-Compliance With Medication to Poor Glycemic Status

“…In this study, the results showed that there is a relationship between the length of suffering from DM and glycemic status (p = 0.01 ; OR = 3.46 ; 95% CI = 1.37-8.69), which means that patients with type 2 DM >5 years have a 3.46 times greater risk of experiencing poor glycemic status than patients with type 2 DM ≤5 years. The results of this study support research from Li et al (2018) that proved that the duration of type 2 DM is associated with poor glycemic control. Every one-year increase in the duration of DM is associated with a 5% reduction in the likelihood of achieving glycemic control targets.…”

Prevalence and predictors of polypharmacy prescription among type 2 diabetes patients at a tertiary care department in Ningbo, China: A retrospective database study

“…In 2015, the T2DM prevalence in adults over 40 years of age in Ningbo was 21% [2]. At a tertiary care department (Department of Endocrinology and Metabolism, Ningbo First Hospital), more than 50% of T2DM patients receiving treatment had poor glycaemic control and vascular complications [3]. The study was conducted at Ningbo First Hospital.…”

Prevalence and associated factors of vascular complications among inpatients with type 2 diabetes: A retrospective database study at a tertiary care department, Ningbo, China

“…In Ningbo, approximately 21% of people over the age of 40 years had T2DM in 2015 [8]. Many patients with T2DM who received treatment at the Department of Endocrinology and Metabolism, Ningbo First Hospital, had poor glycaemic control [9], which could lead to vascular complications.…”